ARHGAP4

Description		Rho GTPase activating protein 4
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Microtubule Growth Cone
	Molecular Function	GTPase Activator Activity Protein Binding Identical Protein Binding
	Biological Process	Cytoskeleton Organization Signal Transduction Rho Protein Signal Transduction Nervous System Development Negative Regulation Of Fibroblast Migration Negative Regulation Of Cell Migration Negative Regulation Of Axon Extension Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Synapse Assembly
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Schizophrenia ( 24043878) Systemic lupus erythematosus ( 26502338)
Interacting Genes		3 interacting genes: MAP3K1 NRAS RAC1
Entrez ID		393
HPRD ID		02063
Ensembl ID		ENSG00000089820
Uniprot IDs		P98171
PDB IDs		2EPD
Enriched GO Terms of Interacting Partners?		Intracellular Signaling Cassette G Protein Activity Positive Regulation Of Ovarian Follicle Development Negative Regulation Of Interleukin-23 Production Regulation Of ERK5 Cascade Angiotensin-activated Signaling Pathway Involved In Heart Process Embryonic Olfactory Bulb Interneuron Precursor Migration Cerebral Cortex GABAergic Interneuron Development Nucleotide Binding MAPK Cascade Intracellular Signal Transduction GTPase Activity Protein-containing Complex Binding Small GTPase-mediated Signal Transduction GTP Binding Kinocilium Regulation Of Ovarian Follicle Development G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Rho GDP-dissociation Inhibitor Binding Auditory Receptor Cell Morphogenesis Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Erythrocyte Enucleation Hepatocyte Growth Factor Receptor Signaling Pathway Regulation Of Cell Adhesion Involved In Heart Morphogenesis Engulfment Of Apoptotic Cell Tangential Migration From The Subventricular Zone To The Olfactory Bulb Regulation Of Neuron Maturation Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Bicellular Tight Junction Assembly Regulation Of Interleukin-23 Production Thioesterase Binding Protein Kinase Binding Positive Regulation Of Receptor Clustering Negative Regulation Of Fibroblast Migration Midbrain Dopaminergic Neuron Differentiation Ruffle Assembly Positive Regulation Of Ruffle Assembly Regulation Of Hydrogen Peroxide Metabolic Process NADPH Oxidase Complex Sphingosine-1-phosphate Receptor Signaling Pathway Sphingolipid Mediated Signaling Pathway Interneuron Migration Regulation Of Receptor Clustering Anatomical Structure Arrangement MAP Kinase Kinase Kinase Activity Fc-epsilon Receptor Signaling Pathway Angiotensin-activated Signaling Pathway Rac Protein Signal Transduction Hyperosmotic Response Respiratory Burst
Tagcloud ?