ONECUT3

Name	one cut homeobox 3
Structure	No pdb structure
Interactors	4 interactors: CIB1 NCK2 SH3RF1 ZMYND12
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways	Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells Regulation of gene expression in early pancreatic precursor cells
GWAS	No GWAS studies recorded
Entrez ID	390874
HPRD ID	18891
Ensembl ID	ENSG00000205922
Uniprot IDs	O60422
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Positive Regulation Of Protein Metabolic Process Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Negative Regulation Of Signal Transduction Signal Complex Assembly Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Signal Transduction Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of T Cell Proliferation Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Translational Initiation In Response To Stress Negative Regulation Of Cell Communication Regulation Of Leukocyte Proliferation Regulation Of T Cell Activation Positive Regulation Of Translation In Response To Stress Cell Motility Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Regulation Of Supramolecular Fiber Organization Regulation Of Mononuclear Cell Proliferation Regulation Of Immune System Process Regulation Of Protein Metabolic Process Negative Regulation Of Signaling Regulation Of Germ Cell Proliferation Thrombopoietin-mediated Signaling Pathway Positive Regulation Of Male Germ Cell Proliferation Cell Projection Endomitotic Cell Cycle Calcium-dependent Protein Kinase Inhibitor Activity Lamellipodium Regulation Of Male Germ Cell Proliferation MAP-kinase Scaffold Activity Regulation Of CD8-positive, Alpha-beta T Cell Proliferation Positive Regulation Of Cell Communication Immunological Synapse Formation Dendritic Spine Development Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Cell Population Proliferation Positive Regulation Of Signaling Filopodium Tip Microtubule Cytoskeleton Organization Negative Regulation Of Megakaryocyte Differentiation Positive Regulation Of MAPK Cascade Positive Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Hemopoiesis Response To Aldosterone Regulation Of CD8-positive, Alpha-beta T Cell Activation Positive Regulation Of Cell Adhesion