SCIMP

Description		SLP adaptor and CSK interacting membrane protein
Image		No pdb structure
GO Annotations	Cellular Component	Ruffle Immunological Synapse Plasma Membrane Membrane Filopodium Leading Edge Membrane Uropod Membrane Cytoplasmic Vesicle Cell Projection Receptor Complex Phagocytic Vesicle Tetraspanin-enriched Microdomain
	Molecular Function	Protein Binding Molecular Adaptor Activity
	Biological Process	Positive Regulation Of Cytokine Production Involved In Immune Response Positive Regulation Of Dendritic Cell Cytokine Production Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Interleukin-12 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Stress-activated MAPK Cascade Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Molecule Of Fungal Origin
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease ( 31473137) Alzheimer's disease (late onset) ( 24162737 30617256) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256)
Interacting Genes		1 interacting genes: MEOX2
Entrez ID		388325
HPRD ID		18267
Ensembl ID		ENSG00000161929
Uniprot IDs		I3L1W2 Q6UWF3
PDB IDs
Enriched GO Terms of Interacting Partners?		Somite Specification Segment Specification Somite Development Embryonic Pattern Specification Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Skeletal Muscle Tissue Development Negative Regulation Of Endothelial Cell Migration Regulation Of Cell Migration Involved In Sprouting Angiogenesis Limb Development Negative Regulation Of Blood Vessel Endothelial Cell Migration Roof Of Mouth Development Regulation Of Blood Vessel Endothelial Cell Migration Striated Muscle Tissue Development Muscle Tissue Development
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