TMEM189

Gene Name		transmembrane protein 189
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: UBE2N
Entrez ID		387521
HPRD ID		17257
Ensembl ID		ENSG00000240849
Uniprot IDs		A5PLL7 Q5TGE2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Histone Ubiquitination DNA Double-strand Break Processing Postreplication Repair Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Protein K63-linked Ubiquitination DNA Catabolic Process, Exonucleolytic Histone Ubiquitination Positive Regulation Of DNA Repair Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of DNA Repair Positive Regulation Of Response To DNA Damage Stimulus MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Histone Modification Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Double-strand Break Repair Via Homologous Recombination Recombinational Repair Regulation Of Ubiquitin-protein Transferase Activity Toll-like Receptor Signaling Pathway T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Histone Modification Regulation Of Response To DNA Damage Stimulus Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Antigen Receptor-mediated Signaling Pathway DNA Catabolic Process Activation Of Innate Immune Response Positive Regulation Of DNA Metabolic Process Double-strand Break Repair Protein Polyubiquitination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Innate Immune Response Intracellular Receptor Signaling Pathway Regulation Of Protein Ubiquitination Regulation Of Chromosome Organization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Fc-epsilon Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling DNA Recombination Regulation Of Innate Immune Response Fc Receptor Signaling Pathway
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