KCTD8

Description		potassium channel tetramerization domain containing 8
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GO Annotations	Cellular Component	Plasma Membrane Membrane Presynaptic Membrane Cell Projection Receptor Complex Synapse Postsynaptic Membrane Presynaptic Active Zone Membrane Postsynapse
	Molecular Function	Protein Binding Identical Protein Binding
	Biological Process	Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4- carriers ( 25778476) Anticoagulant levels ( 22216198) Body size at age 10 ( 32376654) Response to amphetamines ( 22952603) Triglyceride levels in HIV infection ( 33109212) Uterine fibroids ( 30194396)
Novel Interacting Genes		2 novel interacting genes: BEND4 DCAF4L1
Interacting Genes		1 interacting genes: HNRNPK
Entrez ID		386617
HPRD ID		13771
Ensembl ID		ENSG00000183783
Uniprot IDs		Q6ZWB6
PDB IDs		6G57
Enriched GO Terms of Interacting Partners?		Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Low-density Lipoprotein Particle Clearance Negative Regulation Of MRNA Splicing, Via Spliceosome Regulatory NcRNA-mediated Heterochromatin Formation Regulation Of Low-density Lipoprotein Particle Clearance Negative Regulation Of RNA Splicing Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Random Inactivation Of X Chromosome Cul4-RING E3 Ubiquitin Ligase Complex
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