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KRT12
Description
keratin 12
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Cytoskeleton
Intermediate Filament
Keratin Filament
Extracellular Exosome
Molecular Function
Structural Molecule Activity
Structural Constituent Of Skin Epidermis
Biological Process
Morphogenesis Of An Epithelium
Visual Perception
Epithelial Cell Differentiation
Intermediate Filament Organization
Cornea Development In Camera-type Eye
Pathways
Keratinization
Formation of the cornified envelope
Drugs
Griseofulvin
Anthralin
Diseases
Meesmann corneal dystrophy
GWAS
Novel Interacting Genes
2 novel interacting genes:
CLU
ERBB2
Interacting Genes
1 interacting genes:
UCHL5
Entrez ID
3859
HPRD ID
03405
Ensembl ID
ENSG00000187242
Uniprot IDs
Q99456
PDB IDs
Enriched GO Terms of Interacting Partners
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Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Activation Of Membrane Attack Complex
Positive Regulation Of Signal Transduction
Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy
Perinuclear Endoplasmic Reticulum Lumen
Positive Regulation Of Neurofibrillary Tangle Assembly
Leukocyte Proliferation
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Inclusion Body Assembly
Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Complement-dependent Cytotoxicity
Central Nervous System Myelin Maintenance
Neurofibrillary Tangle
Chromaffin Granule
Regulation Of Neuronal Signal Transduction
Positive Regulation Of Amyloid Fibril Formation
Regulation Of Protein Metabolic Process
Immune Complex Clearance
Negative Regulation Of Immature T Cell Proliferation In Thymus
RNA Polymerase I Core Binding
ErbB-3 Class Receptor Binding
ERBB3:ERBB2 Complex
Immature T Cell Proliferation In Thymus
ERBB2-ERBB4 Signaling Pathway
Spherical High-density Lipoprotein Particle
Positive Regulation Of Cell Communication
Signaling Receptor Binding
Microglial Cell Proliferation
Protein Import
Regulation Of Protein Catabolic Process
Positive Regulation Of Signaling
Protein Heterodimerization Activity
Regulation Of Proteolysis
Regulation Of Neurofibrillary Tangle Assembly
Negative Regulation Of Immature T Cell Proliferation
ERBB2-ERBB3 Signaling Pathway
ERBB3 Signaling Pathway
ERBB2-EGFR Signaling Pathway
ERBB4 Signaling Pathway
Forebrain Morphogenesis
Protein Carrier Chaperone
Negative Regulation Of T Cell Differentiation In Thymus
Negative Regulation Of Amyloid Fibril Formation
Protein Targeting To Vacuole Involved In Autophagy
Regulation Of Complement-dependent Cytotoxicity
Negative Regulation Of Complement Activation
Response To Misfolded Protein
Semaphorin Receptor Complex
Regulation Of Immature T Cell Proliferation In Thymus
Positive Regulation Of Telomere Maintenance In Response To DNA Damage
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