KIFC1

Description		kinesin family member C1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Early Endosome Centrosome Microtubule Organizing Center Spindle Cytoskeleton Kinesin Complex Microtubule Membrane Mitotic Spindle
	Molecular Function	Nucleotide Binding Microtubule Motor Activity ATP Binding Microtubule Binding ATP Hydrolysis Activity
	Biological Process	Mitotic Sister Chromatid Segregation Microtubule-based Movement Mitotic Metaphase Chromosome Alignment Spermatogenesis Cell Division Mitotic Spindle Assembly
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730)
Interacting Genes		3 interacting genes: APP CEBPA NKRF
Entrez ID		3833
HPRD ID		18798
Ensembl ID		ENSG00000237649
Uniprot IDs		A0A024RCS7 Q9BW19
PDB IDs		5WDH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Inflammatory Response Regulation Of Response To Calcium Ion Developmental Maturation Amylin Binding Positive Regulation Of Protein Catabolic Process Endosome To Plasma Membrane Transport Vesicle Cell Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Negative Regulation Of DNA-templated Transcription Lipoprotein Particle Memory Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cellular Response To Metal Ion Positive Regulation Of Transcription By RNA Polymerase II CHOP-C/EBP Complex RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Negative Regulation Of RNA Metabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Learning Or Memory Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling White Fat Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription
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