KCNS3

Description		potassium voltage-gated channel modifier subfamily S member 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex
	Molecular Function	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Potassium Channel Regulator Activity
	Biological Process	Action Potential Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Protein Homooligomerization Transmembrane Transport Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Drugs		Enflurane Promethazine Miconazole
Diseases
GWAS		Body fat percentage ( 31752434) Colonoscopy-negative controls vs population controls ( 29228715) Colorectal cancer ( 29228715) Femur bone mineral density x serum urate levels interaction ( 34046847) FEV1 ( 30804560) Height ( 28552196 31562340) Hip circumference adjusted for BMI ( 28552196) Low density lipoprotein cholesterol levels ( 33339817) Lung function (FEV1) ( 26635082 28166213) Lung function (FEV1/FVC) ( 30804560 26635082 28166213) Lung function (FVC) ( 30804560) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Peak expiratory flow ( 30804560) Physiological traits ( 31902109) QT interval (sulfonylurea treatment interaction) ( 27958378) Systolic blood pressure night-to-day ratio in hypertension ( 29973135) Total cholesterol levels ( 33339817) Urate levels in obese individuals ( 25811787)
Interacting Genes		1 interacting genes: KCNB1
Entrez ID		3790
HPRD ID		04865
Ensembl ID		ENSG00000170745
Uniprot IDs		Q9BQ31
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Motor Neuron Apoptotic Process Regulation Of Norepinephrine Secretion Clustering Of Voltage-gated Potassium Channels Positive Regulation Of Catecholamine Secretion Regulation Of Long-term Synaptic Depression Positive Regulation Of Long-term Synaptic Depression Cholinergic Synapse Potassium Ion Export Across Plasma Membrane Neuronal Ion Channel Clustering Positive Regulation Of Calcium Ion-dependent Exocytosis Proximal Dendrite Outward Rectifier Potassium Channel Activity Positive Regulation Of Norepinephrine Secretion Response To L-glutamate Delayed Rectifier Potassium Channel Activity Neuronal Cell Body Membrane Positive Regulation Of Protein Targeting To Membrane Negative Regulation Of Insulin Secretion Regulation Of Protein Targeting To Membrane Cellular Response To Glucose Stimulus Response To Axon Injury Positive Regulation Of Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Dendrite Membrane Negative Regulation Of Hormone Secretion Export Across Plasma Membrane Potassium Channel Regulator Activity Regulation Of Catecholamine Secretion Voltage-gated Potassium Channel Activity Glutamate Receptor Signaling Pathway Regulation Of Calcium Ion-dependent Exocytosis Cellular Response To Carbohydrate Stimulus Negative Regulation Of Peptide Secretion Negative Regulation Of Protein Secretion Lateral Plasma Membrane Potassium Channel Activity Regulation Of Action Potential Postsynaptic Specialization Membrane SNARE Binding Regulation Of Amine Transport Vesicle Docking Voltage-gated Potassium Channel Complex Cellular Response To Calcium Ion Organelle Localization By Membrane Tethering Positive Regulation Of Exocytosis Membrane Docking Intracellular Glucose Homeostasis Sarcolemma Action Potential Response To Amino Acid
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