KCNN1

Description		potassium calcium-activated channel subfamily N member 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Z Disc Neuron Projection Neuronal Cell Body Synapse
	Molecular Function	Inward Rectifier Potassium Channel Activity Calmodulin Binding Calcium-activated Potassium Channel Activity Small Conductance Calcium-activated Potassium Channel Activity
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Chemical Synaptic Transmission Monoatomic Ion Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways		Ca2+ activated K+ channels
Drugs		Procaine Ritodrine Nitrendipine Miconazole Colforsin Trimebutine Rimtuzalcap
Diseases
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Mean reticulocyte volume ( 32888494)
Novel Interacting Genes		1 novel interacting genes: RAB8A
Interacting Genes		5 interacting genes: CALM1 CALM2 CALM3 DSCAM FXR1
Entrez ID		3780
HPRD ID		04282
Ensembl ID		ENSG00000105642
Uniprot IDs		A0A804HIF9 A0A804HIW7 Q92952
PDB IDs
Enriched GO Terms of Interacting Partners?		Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Regulation Of Synaptic Plasticity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Titin Binding Detection Of Calcium Ion Vesicle-mediated Transport In Synapse Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Calyx Of Held Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Transporter Activity Calcium Channel Complex Calcineurin-mediated Signaling Presynaptic Cytosol Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Myelin Sheath Modulation Of Chemical Synaptic Transmission Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of Calcium Ion Transmembrane Transport Spindle Microtubule Presynaptic Endocytosis Substantia Nigra Development Calcium Channel Regulator Activity Sperm Midpiece Negative Regulation Of Calcium Ion Transport G2/M Transition Of Mitotic Cell Cycle Long-term Synaptic Potentiation Sarcomere Cell Cycle G2/M Phase Transition Neural Nucleus Development Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Cation Transmembrane Transport Protein Serine/threonine Kinase Activator Activity Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Monoatomic Ion Transmembrane Transport Voltage-gated Potassium Channel Complex Calcium-dependent Protein Binding Regulation Of Cardiac Muscle Contraction Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Sequestering Of Calcium Ion Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Cytokinesis Negative Regulation Of Voltage-gated Calcium Channel Activity
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