KCNK2

Description		potassium two pore domain channel subfamily K member 2
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Membrane Apical Plasma Membrane Axon Dendrite Node Of Ranvier Sarcolemma Cell Projection Neuronal Cell Body Axon Terminus Calyx Of Held Synapse Postsynaptic Membrane Astrocyte Projection Schaffer Collateral - CA1 Synapse Postsynaptic Density Membrane
	Molecular Function	Voltage-gated Potassium Channel Activity Potassium Channel Activity Outward Rectifier Potassium Channel Activity Potassium Channel Inhibitor Activity Ligand-gated Channel Activity Potassium Ion Leak Channel Activity Identical Protein Binding Metal Ion Binding Protein Heterodimerization Activity Mechanosensitive Potassium Channel Activity
	Biological Process	Cardiac Ventricle Development Monoatomic Ion Transport Potassium Ion Transport G Protein-coupled Receptor Signaling Pathway Memory Response To Mechanical Stimulus Glutamate Secretion Neuronal Action Potential Regulation Of Synaptic Transmission, GABAergic Monoatomic Ion Transmembrane Transport Regulation Of Membrane Potential Response To Axon Injury Detection Of Mechanical Stimulus Involved In Sensory Perception Of Touch Negative Regulation Of Cardiac Muscle Cell Proliferation Cellular Response To Hypoxia Potassium Ion Transmembrane Transport Cochlea Development Chemical Synaptic Transmission, Postsynaptic Positive Regulation Of Cellular Response To Hypoxia Chloride Transmembrane Transport Cellular Response To Arachidonate Negative Regulation Of DNA Biosynthetic Process
Pathways		TWIK related potassium channel (TREK) Phase 4 - resting membrane potential
Drugs		Dofetilide Dronedarone
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness ( 32963231) Cortical thickness (MOSTest) ( 32665545) Lung function (FVC) ( 30061609) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
Novel Interacting Genes		1 novel interacting genes: MARK1
Interacting Genes
Entrez ID		3776
HPRD ID		04450
Ensembl ID		ENSG00000082482
Uniprot IDs		O95069 Q6ZW95 U3N6F0 U3N834
PDB IDs		4TWK
Enriched GO Terms of Interacting Partners?		Tau-protein Kinase Activity Regulation Of Postsynapse Assembly Phosphatidylserine Binding Negative Regulation Of Epithelial To Mesenchymal Transition Establishment Of Mitochondrion Localization Tau Protein Binding Phosphatidic Acid Binding Mitochondrion Localization Phosphatidylinositol-4,5-bisphosphate Binding
Tagcloud ?