STIMATE

Description		STIM activating enhancer
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Cortical Endoplasmic Reticulum Endoplasmic Reticulum-plasma Membrane Contact Site
	Molecular Function	Calcium Channel Regulator Activity Protein Binding
	Biological Process	Store-operated Calcium Entry Activation Of Store-operated Calcium Channel Activity
Pathways
Drugs
Diseases
GWAS		Midgestational total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095)
Interacting Genes		2 interacting genes: CCR4 CFTR
Entrez ID		375346
HPRD ID		14675
Ensembl ID		ENSG00000213533
Uniprot IDs		Q86TL2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Multicellular Organismal-level Homeostasis Regulation Of Enamel Mineralization Membrane Hyperpolarization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Cellular Response To Forskolin Golgi-associated Vesicle Membrane Interneuron Migration Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Tolerance Induction Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Homeostatic Process Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle Docking Cholesterol Transport Clathrin-coated Endocytic Vesicle Membrane
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