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CERKL

Description CERK like autophagy regulator
Image No pdb structure
GO Annotations Cellular Component
  • Photoreceptor Outer Segment
  • Photoreceptor Inner Segment
  • Nucleus
  • Nucleoplasm
  • Nucleolus
  • Cytoplasm
  • Endoplasmic Reticulum
  • Golgi Apparatus
  • Cytosol
  • Membrane
  • Perinuclear Region Of Cytoplasm
Molecular Function
  • Lipid Kinase Activity
  • Protein Binding
  • Kinase Activity
  • Sphingolipid Binding
Biological Process
  • Sphingolipid Metabolic Process
  • Sphingolipid Biosynthetic Process
  • Negative Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
  • Retinitis pigmentosa (RP)
GWAS
  • Lymphocyte count ( 32888494)
  • Metabolite levels ( 23823483)
  • Psychosis proneness (perceptual aberration scale and revised social anhedonia scale) ( 28525603)
  • Response to iloperidone treatment (QT prolongation) ( 18521091)
  • White blood cell count ( 21738480)
Interacting Genes 1 interacting genes: VHL
Entrez ID 375298
HPRD ID 09757
Ensembl ID ENSG00000188452
Uniprot IDs Q49MI3
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Regulation Of Cellular Response To Hypoxia
  • Transcription Elongation Factor Activity
  • Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT
  • Amyloid Fibril Formation
  • Negative Regulation Of Receptor Signaling Pathway Via STAT
  • Negative Regulation Of DNA-templated Transcription, Elongation
  • Protein Serine/threonine Kinase Binding
  • Negative Regulation Of Transcription Elongation By RNA Polymerase II
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© Madhavi K. Ganapathiraju 2012-2025