ITPKB

Gene Name		inositol-trisphosphate 3-kinase B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol
	Molecular Function	Protein Binding Calmodulin Binding ATP Binding Inositol-1,4,5-trisphosphate 3-kinase Activity
	Biological Process	MAPK Cascade Signal Transduction Cell Surface Receptor Signaling Pathway Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Positive Thymic T Cell Selection Positive Regulation Of Ras Protein Signal Transduction Positive Regulation Of Alpha-beta T Cell Differentiation
Pathways		Synthesis of IP3 and IP4 in the cytosol Inositol phosphate metabolism
Drugs
Diseases
GWAS		Subcutaneous adipose tissue ( 22589738)
Protein-protein Interactions		5 interactors: CALM1 GOLGA2 PRKACA PRKCA PSME3
Entrez ID		3707
HPRD ID		00942
Ensembl ID		ENSG00000143772
Uniprot IDs		B2R9J0 P27987
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Rhodopsin Mediated Signaling Pathway Activation Of Adenylate Cyclase Activity Rhodopsin Mediated Signaling Pathway Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Lyase Activity Activation Of Phospholipase C Activity Histone H3-T6 Phosphorylation Regulation Of Adenylate Cyclase Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Phospholipase Activity Phototransduction, Visible Light Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of Phospholipase Activity Regulation Of CAMP Biosynthetic Process Positive Regulation Of Lipase Activity Detection Of Visible Light Cellular Response To Light Stimulus Phototransduction Regulation Of CAMP Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Detection Of Light Stimulus Regulation Of Cellular Ketone Metabolic Process Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Energy Reserve Metabolic Process Cellular Response To Radiation Negative Regulation Of Glucose Import Positive Regulation Of Macrophage Differentiation Regulation Of Muscle Contraction Desmosome Organization Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Heart Contraction Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Detection Of Abiotic Stimulus Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Glucose Transport Regulation Of Platelet Aggregation Mitotic Cell Cycle Response To Fibroblast Growth Factor Platelet Activation
Tagcloud ?		2a 5x accumulated alzheimer amyloid astrogliosis beta40 catalytically dystrophic exacerbated extracellular familial forebrain hyperphosphorylation inositol kinases messenger neurites neuro neuroblastoma overproduction pathology phosphorylates plaque secretase surprisingly tau tetrakisphosphate trisphosphate