ITGB8

Gene Name		integrin, beta 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integrin Complex Cell Surface Integrin Alphav-beta8 Complex Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity Receptor Binding Extracellular Matrix Protein Binding
	Biological Process	Ganglioside Metabolic Process Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Extracellular Matrix Organization Cartilage Development Placenta Blood Vessel Development
Pathways		Molecules associated with elastic fibres Elastic fibre formation Integrin cell surface interactions
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: ITGAV TGFB1 VTN
Entrez ID		3696
HPRD ID		05001
Ensembl ID		ENSG00000105855
Uniprot IDs		B4DHD4 P26012 Q9BUG9
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoderm Development Regulation Of Endocytosis Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Vesicle-mediated Transport Endodermal Cell Differentiation Endoderm Formation Regulation Of Cell Migration Regulation Of Cell Adhesion Regulation Of Cell Motility Regulation Of Phagocytosis Regulation Of Locomotion Regulation Of Cellular Component Movement Positive Regulation Of Transport Negative Regulation Of Protein Metabolic Process Interaction With Host Positive Regulation Of Endocytosis Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Binding Formation Of Primary Germ Layer Cell Growth Negative Regulation Of Entry Of Bacterium Into Host Cell Defense Response To Fungus, Incompatible Interaction Entry Of Symbiont Into Host Cell By Promotion Of Host Phagocytosis Positive Regulation Of NAD+ ADP-ribosyltransferase Activity Cell Adhesion Cell-matrix Adhesion Regulation Of Cellular Response To Growth Factor Stimulus Gastrulation Viral Life Cycle Vesicle-mediated Transport Regulation Of Entry Of Bacterium Into Host Cell Active Induction Of Host Immune Response By Virus Cell-substrate Adhesion MAPK Cascade Negative Regulation Of Locomotion Negative Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Hyaluronan Biosynthetic Process Macrophage Derived Foam Cell Differentiation Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Binding Tissue Development Signal Transduction By Phosphorylation Negative Regulation Of Macrophage Cytokine Production Ossification Involved In Bone Remodeling Tolerance Induction To Self Antigen
Tagcloud ?		abcg2 agilent amplifying beta8 cepc cepcs connexin corneal cryosections dissociated epithelia genespring gx11 holoclone lentiviral limbal locked lpc mann micrornas oligo organotypic parabasal progenies rim scrambled transit v2 whitney