LILRA5

Description		leukocyte immunoglobulin like receptor A5
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Cell Surface Membrane
	Molecular Function	Inhibitory MHC Class I Receptor Activity
	Biological Process	Immune System Process Immune Response-regulating Signaling Pathway Cytokine-mediated Signaling Pathway Negative Regulation Of Interleukin-12 Production Negative Regulation Of Interleukin-13 Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of MAPK Cascade Innate Immune Response Positive Regulation Of Inflammatory Response Positive Regulation Of Cell Activation Positive Regulation Of Calcium Ion Transport Positive Regulation Of Protein Tyrosine Kinase Activity
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) HDL cholesterol ( 25961943) High density lipoprotein cholesterol levels ( 33339817)
Novel Interacting Genes		1 novel interacting genes: DNAAF3
Interacting Genes
Entrez ID		353514
HPRD ID		06924
Ensembl ID		ENSG00000187116
Uniprot IDs		A6NI73
PDB IDs		2D3V
Enriched GO Terms of Interacting Partners?		Dynein Axonemal Particle Axonemal Dynein Complex Assembly Motile Cilium Assembly Extracellular Transport Epithelial Cilium Movement Involved In Extracellular Fluid Movement Cerebrospinal Fluid Circulation Seminiferous Tubule Development Determination Of Adult Lifespan Lung Development Male Gonad Development Determination Of Bilateral Symmetry Multicellular Organism Growth Determination Of Left/right Symmetry Gonad Development Cell Morphogenesis Cilium Movement Reproductive Structure Development Microtubule-based Transport Tube Development Brain Development Heart Development Cilium Assembly Cilium Organization Pattern Specification Process Microtubule-based Movement Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Developmental Growth
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