ACADS

Gene Name		acyl-CoA dehydrogenase, C-2 to C-3 short chain
Image
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Mitochondrial Membrane
	Molecular Function	Fatty-acyl-CoA Binding Acyl-CoA Dehydrogenase Activity Butyryl-CoA Dehydrogenase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase Response To Starvation Cellular Lipid Metabolic Process Small Molecule Metabolic Process Butyrate Catabolic Process Protein Homotetramerization Response To Glucocorticoid
Pathways		Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Mitochondrial Fatty Acid Beta-Oxidation mitochondrial fatty acid beta-oxidation of saturated fatty acids Beta oxidation of hexanoyl-CoA to butanoyl-CoA Beta oxidation of butanoyl-CoA to acetyl-CoA
Drugs		NADH Acetoacetyl-Coenzyme A Flavin-Adenine Dinucleotide
Diseases
GWAS		Metabolic traits ( 21886157) Metabolite levels ( 20037589)
Protein-protein Interactions		1 interactors: IRF7
Entrez ID		35
HPRD ID		06053
Ensembl ID		ENSG00000122971
Uniprot IDs		E5KSD5 E9PE82 P16219
PDB IDs		2VIG
Enriched GO Terms of Interacting Partners?		Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway MDA-5 Signaling Pathway Interferon-beta Production Interferon-alpha Production Negative Regulation Of Macrophage Apoptotic Process Regulation Of MyD88-dependent Toll-like Receptor Signaling Pathway Cytoplasmic Pattern Recognition Receptor Signaling Pathway In Response To Virus Establishment Of Viral Latency Type I Interferon Biosynthetic Process Positive Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Monocyte Differentiation Type I Interferon Production Cellular Response To Virus Regulation Of Macrophage Apoptotic Process Negative Regulation Of Myeloid Cell Apoptotic Process Positive Regulation Of Interferon-alpha Production Cytokine Biosynthetic Process Positive Regulation Of Interferon-beta Production Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Cytokine Metabolic Process Regulation Of Myeloid Cell Apoptotic Process Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Interferon-beta Production Negative Regulation Of Leukocyte Apoptotic Process Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Type I Interferon Production Toll-like Receptor 4 Signaling Pathway Regulation Of Cytokine-mediated Signaling Pathway Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Response To Type I Interferon Regulation Of Myeloid Leukocyte Differentiation Interferon-gamma-mediated Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cytokine Production Activation Of Innate Immune Response Cellular Response To Interferon-gamma Defense Response To Virus Response To Interferon-gamma Regulation Of Myeloid Cell Differentiation Immunoglobulin Mediated Immune Response B Cell Mediated Immunity
Tagcloud ?		accumulate acyl ammonia anaerobic bona coa dehydrogenases etf fide flavoprotein intermediates lymphoblast mcad mum octanoyl phenylacetyl phenylbutyrate phenylbutyryl phenylpropionyl playing postulated reductive round sec straight ternary titration undetectable utilize