GEN1

Description		GEN1 Holliday junction 5' flap endonuclease
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome
	Molecular Function	Magnesium Ion Binding Four-way Junction DNA Binding DNA Binding Catalytic Activity Nuclease Activity Endonuclease Activity Crossover Junction DNA Endonuclease Activity Hydrolase Activity 5'-flap Endonuclease Activity Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination DNA Damage Response Regulation Of Centrosome Duplication Replication Fork Processing Resolution Of DNA Recombination Intermediates Resolution Of Mitotic Recombination Intermediates Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Pathways		Resolution of D-loop Structures through Holliday Junction Intermediates
Drugs
Diseases
GWAS
Interacting Genes		1 interacting genes: HUNK
Entrez ID		348654
HPRD ID		08813
Ensembl ID		ENSG00000178295
Uniprot IDs		Q17RS7
PDB IDs		5T9J
Enriched GO Terms of Interacting Partners?
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