CTU2

Description		cytosolic thiouridylase subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	TRNA Binding Protein Binding Nucleotidyltransferase Activity Sulfurtransferase Activity
	Biological Process	TRNA Wobble Uridine Modification TRNA Wobble Position Uridine Thiolation TRNA Processing Protein Urmylation TRNA Thio-modification
Pathways		tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Autism spectrum disorder-related traits ( 25534755) Glycated hemoglobin levels ( 34059833) Hair color ( 26926045) Hemoglobin ( 32888494) High light scatter reticulocyte percentage of red cells ( 27863252) Hip circumference adjusted for BMI ( 34021172) Plateletcrit ( 27863252) Pursuit maintenance gain ( 29064472) Reticulocyte fraction of red cells ( 27863252) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		2 interacting genes: OGT WEE2-AS1
Entrez ID		348180
HPRD ID		18372
Ensembl ID		ENSG00000174177
Uniprot IDs		H3BSW6 Q2VPK5
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Pre-mRNA 5'-splice Site Binding MRNA 5'-splice Site Recognition Regulation Of Transcription By Glucose NSL Complex Acetylglucosaminyltransferase Activity Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane U1 SnRNP Sin3-type Complex Histone Acetyltransferase Complex Negative Regulation Of Stem Cell Population Maintenance Regulation Of Protein Localization To Synapse Regulation Of Receptor Localization To Synapse Regulation Of Necroptotic Process Regulation Of Rac Protein Signal Transduction MRNA Splice Site Recognition Phosphatidylinositol-3,4,5-trisphosphate Binding Cellular Response To Nutrient Regulation Of Programmed Necrotic Cell Death Mitophagy Protein Localization To Lysosome Circadian Regulation Of Gene Expression Positive Regulation Of Stem Cell Population Maintenance Cellular Response To Glucose Stimulus Regulation Of Stem Cell Population Maintenance Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Carbohydrate Catabolic Process Regulation Of Gluconeogenesis Regulation Of ATP Metabolic Process Regulation Of Glycolytic Process Positive Regulation Of TORC1 Signaling Cellular Response To Carbohydrate Stimulus Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Protein Catabolic Process Pyroptotic Inflammatory Response Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Autophagy Of Mitochondrion Positive Regulation Of Translational Initiation Protein-containing Complex Organization Negative Regulation Of Protein Ubiquitination Protein-containing Complex Assembly TORC1 Signaling Regulation Of Insulin Receptor Signaling Pathway
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