TREML1

Gene Name		triggering receptor expressed on myeloid cells-like 1
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane Platelet Alpha Granule
	Molecular Function	Protein Binding
	Biological Process	Calcium-mediated Signaling Platelet Activation Innate Immune Response
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: PTPN11 PTPN6
Entrez ID		340205
HPRD ID		11645
Ensembl ID		ENSG00000161911
Uniprot IDs		Q86YW5
PDB IDs		2FRG
Enriched GO Terms of Interacting Partners?		Abortive Mitotic Cell Cycle Megakaryocyte Development Platelet Formation Platelet Morphogenesis Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Megakaryocyte Differentiation Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Type I Interferon-mediated Signaling Pathway T Cell Costimulation Regulation Of Cytokine-mediated Signaling Pathway Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Type I Interferon Interferon-gamma-mediated Signaling Pathway Cellular Response To Interferon-gamma Hematopoietic Progenitor Cell Differentiation Response To Interferon-gamma Peptidyl-tyrosine Dephosphorylation Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Adhesion Positive Regulation Of T Cell Activation Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Positive Regulation Of Homotypic Cell-cell Adhesion Leukocyte Migration Bone Development Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Myeloid Cell Differentiation Protein Dephosphorylation Regulation Of MAP Kinase Activity Regulation Of T Cell Activation Positive Regulation Of Cell Activation Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Negative Regulation Of Glucocorticoid Secretion Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Regulation Of Mitotic Cell Cycle Blood Coagulation Hemostasis Regulation Of Intracellular Transport Cytokine-mediated Signaling Pathway Response To Peptide Hormone Negative Regulation Of B Cell Receptor Signaling Pathway Dephosphorylation Immune Response-regulating Signaling Pathway
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