METTL2A

Description		methyltransferase 2A, tRNA N3-cytidine
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Binding Methyltransferase Activity RNA Methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity Transferase Activity TRNA (cytidine-3-)-methyltransferase Activity
	Biological Process	TRNA Metabolic Process TRNA Modification TRNA Processing TRNA Methylation Methylation
Pathways
Drugs
Diseases
GWAS		Objective response to lithium treatment ( 26503763)
Interacting Genes		2 interacting genes: CFTR MAPK6
Entrez ID		339175
HPRD ID		07795
Ensembl ID		ENSG00000087995
Uniprot IDs		B3KM33 Q96IZ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Septin Cytoskeleton Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Protein-containing Complex MAP Kinase Activity Chloride Transmembrane Transporter Activity Sperm Capacitation Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Positive Regulation Of Dendritic Spine Development Sterol Biosynthetic Process Chloride Channel Complex Positive Regulation Of Developmental Process Positive Regulation Of Biomineral Tissue Development Regulation Of Dendritic Spine Development ATP Binding Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle Docking Cholesterol Transport Clathrin-coated Endocytic Vesicle Membrane
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