RAB43

Description		RAB43, member RAS oncogene family
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Endomembrane System Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Cis-Golgi Network Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Phagocytic Vesicle Extracellular Exosome
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding
	Biological Process	Autophagosome Assembly Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Virion Assembly Retrograde Transport, Plasma Membrane To Golgi Cellular Response To Type II Interferon Phagosome Maturation Regulation Of Golgi Organization
Pathways		Retrograde transport at the Trans-Golgi-Network RAB geranylgeranylation
Drugs
Diseases
GWAS		Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		2 interacting genes: APP CRYAA
Entrez ID		339122
HPRD ID		17947
Ensembl ID		ENSG00000172780
Uniprot IDs		Q86YS6
PDB IDs		2HUP
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Light Stimulus Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Response To Radiation Axon Choice Point Recognition Supramolecular Fiber Organization Lens Fiber Cell Morphogenesis Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Apoptotic Process Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Regulation Of Growth Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding
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