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RAB7B
Description
RAB7B, member RAS oncogene family
Image
No pdb structure
GO Annotations
Cellular Component
Lysosome
Endosome
Late Endosome
Golgi Apparatus
Trans-Golgi Network
Membrane
Phagocytic Vesicle Membrane
Organelle Membrane
Cytoplasmic Vesicle
Late Endosome Membrane
Phagocytic Vesicle
Molecular Function
Nucleotide Binding
GTPase Activity
Protein Binding
GTP Binding
Biological Process
Regulation Of Immune System Process
Endosome To Lysosome Transport
Protein Transport
Positive Regulation Of Interleukin-6 Production
Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
Negative Regulation Of Toll-like Receptor 9 Signaling Pathway
Late Endosome To Golgi Transport
Positive Regulation Of Megakaryocyte Differentiation
Positive Regulation Of NF-kappaB Transcription Factor Activity
Cellular Response To Type II Interferon
Phagosome-lysosome Fusion
Pathways
TBC/RABGAPs
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS
Interacting Genes
3 interacting genes:
APP
APPBP2
RAP1B
Entrez ID
338382
HPRD ID
15202
Ensembl ID
ENSG00000276600
Uniprot IDs
A0A096LP44
Q96AH8
PDB IDs
Enriched GO Terms of Interacting Partners
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Amyloid-beta Complex
Growth Cone Lamellipodium
Regulation Of Response To Calcium Ion
Amylin Binding
Positive Regulation Of Toll Signaling Pathway
Cellular Response To CAMP
Response To CAMP
Acetylcholine Receptor Activator Activity
Membrane Raft
PTB Domain Binding
Response To Purine-containing Compound
Collateral Sprouting In Absence Of Injury
Regulation Of Protein Import
Endosome To Plasma Membrane Transport Vesicle
Positive Regulation Of Endothelin Production
Growth Cone Filopodium
Lipoprotein Particle
Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Protein Import
Microglia Development
Positive Regulation Of G Protein-coupled Receptor Internalization
Positive Regulation Of ERK1 And ERK2 Cascade
Regulation Of Cell Junction Assembly
Response To Norepinephrine
Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Intermediate-density Lipoprotein Particle
Regulation Of ERK1 And ERK2 Cascade
Axon Midline Choice Point Recognition
Positive Regulation Of Amyloid Fibril Formation
Cellular Response To Norepinephrine Stimulus
Growth Factor Receptor Binding
Main Axon
Astrocyte Activation Involved In Immune Response
Low-density Lipoprotein Particle Mediated Signaling
Establishment Of Localization In Cell
Synapse Organization
Regulation Of Spontaneous Synaptic Transmission
NMDA Selective Glutamate Receptor Signaling Pathway
Regulation Of Synapse Structure Or Activity
Regulation Of Toll Signaling Pathway
Negative Regulation Of Synaptic Vesicle Exocytosis
Axon Choice Point Recognition
Heparan Sulfate Binding
Signaling Receptor Activator Activity
Peptidase Activator Activity
Cellular Response To Manganese Ion
Negative Regulation Of Calcium Ion-dependent Exocytosis
Rap Protein Signal Transduction
Antifungal Humoral Response
Nuclear Envelope Lumen
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