NLRP10

Description		NLR family pyrin domain containing 10
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Nuclear Membrane
	Molecular Function	Nucleotide Binding GTPase Activity ATP Binding ATP Hydrolysis Activity
	Biological Process	Activation Of Innate Immune Response Adaptive Immune Response Immune System Process Positive Regulation Of T-helper 1 Type Immune Response Inflammatory Response Positive Regulation Of Defense Response Positive Regulation Of Interleukin-1 Alpha Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Interleukin-8 Production Innate Immune Response Regulation Of Inflammatory Response Positive Regulation Of Inflammatory Response Positive Regulation Of Immune Response Defense Response To Fungus Positive Regulation Of Defense Response To Bacterium Positive Regulation Of T-helper 17 Type Immune Response
Pathways
Drugs
Diseases
GWAS		Atopic dermatitis ( 23042114) Malaria ( 31844061) Response to anti-TNF therapy in rheumatoid arthritis ( 26776603)
Interacting Genes		1 interacting genes: AR
Entrez ID		338322
HPRD ID		14802
Ensembl ID		ENSG00000182261
Uniprot IDs		Q86W26
PDB IDs		2M5V
Enriched GO Terms of Interacting Partners?		Lateral Sprouting Involved In Mammary Gland Duct Morphogenesis Prostate Induction Male Genitalia Morphogenesis POU Domain Binding Tertiary Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Male Somatic Sex Determination Positive Regulation Of Integrin Biosynthetic Process Androgen Binding Regulation Of Prostatic Bud Formation RNA Polymerase II General Transcription Initiation Factor Binding Cellular Response To Testosterone Stimulus Genitalia Morphogenesis Lateral Sprouting From An Epithelium Leydig Cell Differentiation Estrogen Response Element Binding Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Prostate Gland Growth Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Epithelial Cell Differentiation Involved In Prostate Gland Development Male Sex Determination Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase III Cellular Response To Estrogen Stimulus Mammary Gland Alveolus Development Morphogenesis Of An Epithelial Fold Sex Determination Organ Induction RNA Polymerase II Core Promoter Sequence-specific DNA Binding Seminiferous Tubule Development Prostate Gland Epithelium Morphogenesis Reproductive System Development Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Nuclear Steroid Receptor Activity Animal Organ Formation Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Transcription By RNA Polymerase III Steroid Binding Regulation Of Animal Organ Formation Developmental Induction Insulin-like Growth Factor Receptor Signaling Pathway Epithelial Cell Morphogenesis Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Morphogenesis Of An Epithelium Response To Testosterone Regulation Of Systemic Arterial Blood Pressure Organ Growth Molecular Condensate Scaffold Activity Transcription Coactivator Binding
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