HTR1F

Gene Name		5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Serotonin Receptor Activity Serotonin Binding
	Biological Process	G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Serotonin Receptor Signaling Pathway Synaptic Transmission
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Class A/1 (Rhodopsin-like receptors) Amine ligand-binding receptors G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Serotonin receptors
Drugs		Eletriptan Zolmitriptan Sumatriptan Naratriptan Rizatriptan
Diseases
GWAS
Protein-protein Interactions		1 interactors: CAV1
Entrez ID		3355
HPRD ID		01637
Ensembl ID
Uniprot IDs		P30939
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Nitric Oxide Homeostasis Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Inward Rectifier Potassium Channel Activity Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Negative Regulation Of Pinocytosis Caveolin-mediated Endocytosis Protein Localization To Basolateral Plasma Membrane Mammary Gland Involution Protein Localization To Plasma Membrane Raft Positive Regulation Of Metalloenzyme Activity Caveola Assembly Regulation Of Cardiac Muscle Cell Action Potential Regulation Of The Force Of Heart Contraction By Chemical Signal Negative Regulation Of Nitric-oxide Synthase Activity Cellular Response To Hyperoxia Membrane Raft Assembly Protein Localization To Membrane Raft Negative Regulation Of Monooxygenase Activity Negative Regulation Of Protein Autophosphorylation Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Anoikis Negative Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Anoikis Membrane Raft Organization Negative Regulation Of JAK-STAT Cascade Membrane Assembly Regulation Of Membrane Repolarization Negative Regulation Of Potassium Ion Transport Negative Regulation Of Oxidoreductase Activity Membrane Biogenesis Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Potassium Ion Transmembrane Transporter Activity Nitric Oxide Metabolic Process Regulation Of Protein Autophosphorylation Reactive Nitrogen Species Metabolic Process Regulation Of The Force Of Heart Contraction Inactivation Of MAPK Activity Positive Regulation Of Vasoconstriction Negative Regulation Of Endothelial Cell Proliferation Vasoconstriction Response To Hyperoxia Response To Ischemia Negative Regulation Of Epithelial Cell Differentiation Positive Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Cytokine-mediated Signaling Pathway
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