HTR1F

Description		5-hydroxytryptamine receptor 1F
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GO Annotations	Cellular Component	Plasma Membrane Membrane Dendrite Synapse
	Molecular Function	Gi/o-coupled Serotonin Receptor Activity G Protein-coupled Receptor Activity G Protein-coupled Serotonin Receptor Activity Neurotransmitter Receptor Activity Serotonin Binding Serotonin Receptor Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway Chemical Synaptic Transmission
Pathways		Serotonin receptors G alpha (i) signalling events
Drugs		Eletriptan Methysergide Zolmitriptan Dihydroergotamine Olanzapine Sumatriptan Ergotamine Paroxetine Naratriptan Rizatriptan Ergoloid mesylate Ketamine Chlorprothixene Mianserin Setiptiline Dihydroergocornine Lasmiditan Gilteritinib Lecozotan Tiapride Dihydroergocristine
Diseases
GWAS
Interacting Genes		1 interacting genes: CAV1
Entrez ID		3355
HPRD ID		01637
Ensembl ID		ENSG00000179097
Uniprot IDs		P30939
PDB IDs		7EXD
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Nitric Oxide Biosynthetic Process Nitric-oxide Synthase Binding Regulation Of Entry Of Bacterium Into Host Cell Receptor-mediated Endocytosis Of Virus By Host Cell Peptidase Activator Activity Membrane Raft Assembly Inward Rectifier Potassium Channel Inhibitor Activity Response To Misfolded Protein Caveola Assembly Protein Tyrosine Kinase Inhibitor Activity Cellular Response To Increased Oxygen Levels Positive Regulation Of Calcium Ion Transport Into Cytosol Insulin Receptor Internalization Protein Localization To Basolateral Plasma Membrane Protein Localization To Plasma Membrane Raft Intracellular Nitric Oxide Homeostasis Nitric-oxide Synthase Inhibitor Activity Caveolin-mediated Endocytosis Plasma Membrane Raft Assembly Regulation Of Membrane Repolarization During Action Potential Regulation Of Ventricular Cardiac Muscle Cell Action Potential Caveolar Macromolecular Signaling Complex Protein Localization To Membrane Raft Plasma Membrane Raft Organization Regulation Of Gap Junction Assembly Endocytosis Involved In Viral Entry Into Host Cell Positive Regulation Of Gap Junction Assembly Negative Regulation Of Pinocytosis Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Mammary Gland Involution Patched Binding Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Oxysterol Binding Regulation Of The Force Of Heart Contraction By Chemical Signal Cellular Response To Misfolded Protein Cellular Response To Hyperoxia Regulation Of Cell Communication By Electrical Coupling Response To Hyperoxia Negative Regulation Of Anoikis Positive Regulation Of ERAD Pathway Negative Regulation Of Necroptotic Process Angiotensin-activated Signaling Pathway Regulation Of Calcium Ion Transport Into Cytosol Acrosomal Membrane Glandular Epithelial Cell Differentiation Regulation Of The Force Of Heart Contraction Negative Regulation Of Programmed Necrotic Cell Death Muscle Cell Cellular Homeostasis Membrane Raft Organization Cellular Response To Topologically Incorrect Protein
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