HTR1E

Description		5-hydroxytryptamine receptor 1E
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GO Annotations	Cellular Component	Plasma Membrane Membrane Dendrite Synapse
	Molecular Function	Gi/o-coupled Serotonin Receptor Activity G Protein-coupled Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity Serotonin Binding Serotonin Receptor Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway Chemical Synaptic Transmission
Pathways		Serotonin receptors G alpha (i) signalling events
Drugs		Ziprasidone Methysergide Zolmitriptan Dihydroergotamine Olanzapine Clozapine Loxapine Paroxetine Ergoloid mesylate Ketamine Quetiapine Aripiprazole Chlorprothixene Setiptiline Dihydroergocornine Gilteritinib Lecozotan Tiapride Dihydroergocristine Aripiprazole lauroxil
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872) Colorectal cancer ( 34062886) Interstitial lung abnormalities ( 31339356) Lung cancer in ever smokers ( 28604730) Prudent dietary pattern ( 28644415) Spontaneous preterm birth without premature rupture of membranes ( 31194736) Subpleural-predominant interstitial lung abnormalities ( 31339356)
Interacting Genes		1 interacting genes: MEOX2
Entrez ID		3354
HPRD ID		01635
Ensembl ID		ENSG00000168830
Uniprot IDs		P28566
PDB IDs		7E33 8UGY 8UH3
Enriched GO Terms of Interacting Partners?		Somite Specification Segment Specification Somite Development Embryonic Pattern Specification Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Skeletal Muscle Tissue Development Negative Regulation Of Endothelial Cell Migration Regulation Of Cell Migration Involved In Sprouting Angiogenesis Limb Development Negative Regulation Of Blood Vessel Endothelial Cell Migration Roof Of Mouth Development Regulation Of Blood Vessel Endothelial Cell Migration Striated Muscle Tissue Development Muscle Tissue Development
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