HSD11B2

Description		hydroxysteroid 11-beta dehydrogenase 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Steroid Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor NAD Binding 11-beta-hydroxysteroid Dehydrogenase (NAD+) Activity
	Biological Process	Response To Hypoxia Regulation Of Blood Volume By Renal Aldosterone Lipid Metabolic Process Female Pregnancy Steroid Metabolic Process Glucocorticoid Metabolic Process Response To Xenobiotic Stimulus Response To Food Response To Insulin Cortisol Metabolic Process Response To Steroid Hormone Response To Glucocorticoid
Pathways		Glucocorticoid biosynthesis Prednisone ADME
Drugs		NADH Fluoxymesterone Formebolone Hydrocortisone aceponate Hydrocortisone acetate Hydrocortisone butyrate Hydrocortisone cypionate Hydrocortisone phosphate Hydrocortisone probutate Hydrocortisone valerate
Diseases		Apparent mineralocorticoid excess syndrome; 11-beta-ketoreductase deficiency
GWAS		Empathy quotient ( 29527006) Refractive error ( 32231278) Waist-to-hip ratio adjusted for body mass index ( 28430825)
Interacting Genes		2 interacting genes: KAT2A KAT2B
Entrez ID		3291
HPRD ID		01958
Ensembl ID		ENSG00000176387
Uniprot IDs		P80365
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H3K9 Acetyltransferase Activity Negative Regulation Of Centriole Replication Internal Peptidyl-lysine Acetylation Histone H3 Acetyltransferase Activity Internal Protein Amino Acid Acetylation Negative Regulation Of Centrosome Duplication Peptidyl-lysine Acetylation ATAC Complex Acetyltransferase Activity Histone Acetyltransferase Complex SAGA Complex Positive Regulation Of Gluconeogenesis Regulation Of Centriole Replication Protein-lysine-acetyltransferase Activity Histone Acetyltransferase Activity Protein Acetylation Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Positive Regulation Of Glucose Metabolic Process Gluconeogenesis Regulation Of Centrosome Duplication Regulation Of Gluconeogenesis Limb Development Regulation Of Centrosome Cycle Hexose Biosynthetic Process Regulation Of Embryonic Development Regulation Of Glucose Metabolic Process Carbohydrate Biosynthetic Process Negative Regulation Of Small Molecule Metabolic Process Memory Glucose Metabolic Process Histone Deacetylase Binding Mitotic Spindle Acyltransferase Activity Negative Regulation Of Cytoskeleton Organization Positive Regulation Of Small Molecule Metabolic Process Hexose Metabolic Process Regulation Of RNA Splicing Regulation Of Cell Division Monosaccharide Metabolic Process Peptidyl-lysine Glutarylation Histone Glutaryltransferase Activity Histone Succinyltransferase Activity DNA-binding Transcription Factor Binding Peptide Glutaryltransferase Activity Regulation Of DNA Repair Regulation Of Organelle Assembly Regulation Of Microtubule-based Process Negative Regulation Of RRNA Processing Heart Development Learning Or Memory
Tagcloud ?