HPGD

Gene Name		hydroxyprostaglandin dehydrogenase 15-(NAD)
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Gene Ontology Annotations	Cellular Component	Cytosol Basolateral Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Catalytic Activity Prostaglandin E Receptor Activity 15-hydroxyprostaglandin Dehydrogenase (NAD+) Activity Protein Homodimerization Activity NAD Binding NAD+ Binding
	Biological Process	Prostaglandin Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Female Pregnancy Parturition Arachidonic Acid Metabolic Process Cyclooxygenase Pathway Lipoxygenase Pathway Ovulation Small Molecule Metabolic Process Negative Regulation Of Cell Cycle Oxidation-reduction Process Thrombin Receptor Signaling Pathway Ductus Arteriosus Closure Lipoxin Metabolic Process
Pathways		Arachidonic acid metabolism Metabolism of lipids and lipoproteins Synthesis of Lipoxins (LX) Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs		NADH
Diseases
GWAS
Protein-protein Interactions		1 interactors: APP
Entrez ID		3248
HPRD ID		03406
Ensembl ID		ENSG00000164120
Uniprot IDs		P15428
PDB IDs		2GDZ
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth RNA 3'-end Processing Cholesterol Metabolic Process Adult Locomotory Behavior Positive Regulation Of Mitotic Cell Cycle Regulation Of Receptor Activity Cell Recognition
Tagcloud ?		11beta 9alpha abcc4 akr1b1 akr1c1 akr1c3 catalyze diseased endometriosis endometriotic endometrium gynecological hieec hiesc hpgds infertility peritoneal pgd2 pgf2alpha pgh2 pla2g2a pla2g4a provokes ptgds ptgfr ptgs2 reaches slco2a synthases