HOXD13

Description		homeobox D13
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Skeletal System Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Pattern Specification Process Anterior/posterior Pattern Specification Gland Morphogenesis Embryonic Limb Morphogenesis Male Genitalia Development Prostate Gland Development Response To Testosterone Limb Morphogenesis Regulation Of Cell Population Proliferation Embryonic Digit Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Hindgut Morphogenesis Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Morphogenesis Of An Epithelial Fold Branch Elongation Of An Epithelium Regulation Of Branching Involved In Prostate Gland Morphogenesis
Pathways
Drugs
Diseases		Synpolydactyly Syndactyly Brachydactyly, including: type A; type B; type D; type E Brachydactyly-syndactyly syndrome
GWAS		Male-pattern baldness ( 28196072)
Interacting Genes		5 interacting genes: CREBBP MEIS1 SMAD1 SMAD2 SMAD5
Entrez ID		3239
HPRD ID		00872
Ensembl ID		ENSG00000128714
Uniprot IDs		P35453
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Regulator Complex Heteromeric SMAD Protein Complex Embryonic Pattern Specification SMAD Protein Complex I-SMAD Binding SMAD Protein Signal Transduction Homomeric SMAD Protein Complex Ureteric Bud Development Mesonephric Epithelium Development Osteoblast Fate Commitment Mesonephric Tubule Development Anti-Mullerian Hormone Receptor Signaling Pathway Kidney Epithelium Development Chromatin Pattern Specification Process Positive Regulation Of Transcription By RNA Polymerase II Transforming Growth Factor Beta Receptor Signaling Pathway DEAD/H-box RNA Helicase Binding Anatomical Structure Morphogenesis Co-SMAD Binding Primary MiRNA Processing Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Cardiac Conduction System Development Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Fate Commitment Positive Regulation Of RNA Metabolic Process Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Nucleobase-containing Compound Metabolic Process Tube Development Epithelium Development Intracellular Signaling Cassette MiRNA Processing RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Ubiquitin Protein Ligase Binding Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Tau Protein Binding Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Male Germ Cell Nucleus Positive Regulation Of Biosynthetic Process Cardiac Muscle Tissue Development DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Intracellular Iron Ion Homeostasis Bone Development Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Chromatin Binding
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