HOXC5

Description		homeobox C5
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cell Junction
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Embryonic Skeletal System Development
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Appendicular lean mass ( 33097823) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		11 interacting genes: CTBP2 DVL3 GORASP2 LHX3 LHX4 PBX1 PBX2 PBX4 POLR2G POU6F2 ZBTB16
Entrez ID		3222
HPRD ID		00859
Ensembl ID		ENSG00000172789
Uniprot IDs		Q00444
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Medial Motor Column Neuron Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Chromatin Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Coregulator Binding Positive Regulation Of Transcription By RNA Polymerase II Transcription Corepressor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Animal Organ Morphogenesis Positive Regulation Of Metabolic Process Regulation Of Gene Expression Embryonic Limb Morphogenesis Regionalization DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process DNA-binding Transcription Factor Activity Limb Morphogenesis RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Eye Development Cellular Developmental Process Regulation Of Macromolecule Metabolic Process Pattern Specification Process DNA Binding Animal Organ Development Anatomical Structure Morphogenesis Motor Neuron Axon Guidance Embryonic Organ Development Proximal/distal Pattern Formation Sequence-specific DNA Binding Sensory Organ Development Neuron Development DNA-binding Transcription Factor Binding Regulation Of Metabolic Process Cell Differentiation In Spinal Cord Placenta Development Brain Development Transcription Regulator Complex Developmental Process Transcription Repressor Complex
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