HOXB4

Description		homeobox B4
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Centrosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Morphogenesis Of An Epithelial Sheet Regulation Of DNA-templated Transcription Anterior/posterior Pattern Specification Hemopoiesis Positive Regulation Of Transcription By RNA Polymerase II Somatic Stem Cell Division Spleen Development Bone Marrow Development Embryonic Skeletal System Morphogenesis Skeletal System Morphogenesis Definitive Hemopoiesis Hematopoietic Stem Cell Differentiation Hematopoietic Stem Cell Proliferation Positive Regulation Of Stem Cell Differentiation
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis Formation of the nephric duct
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		3 interacting genes: CREBBP EP300 MEIS1
Entrez ID		3214
HPRD ID		07032
Ensembl ID		ENSG00000182742
Uniprot IDs		P17483
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Histone H3K27 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Acetylation N-terminal Protein Amino Acid Acetylation Regulation Of Cellular Response To Heat Transcription Regulator Complex Acetyltransferase Activity Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Megakaryocyte Development Histone Acetyltransferase Complex Protein-lysine-acetyltransferase Activity Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone Acetyltransferase Activity Protein Acetylation Tau Protein Binding Chromatin Binding Transcription Coactivator Binding Protein Destabilization Canonical NF-kappaB Signal Transduction Damaged DNA Binding Myeloid Cell Development P53 Binding Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Cellular Response To UV Chromatin DNA Binding Positive Regulation Of Protein Localization To Nucleus Cellular Response To Light Stimulus Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transcription Coregulator Activity Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Acyltransferase Activity Response To UV Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Chromatin Regulation Of Protein Localization To Nucleus Cellular Response To Radiation Innate Immune Response-activating Signaling Pathway DNA-binding Transcription Factor Binding Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding
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