HMGCS2

Gene Name		3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
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Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Hydroxymethylglutaryl-CoA Synthase Activity
	Biological Process	Cholesterol Biosynthetic Process Isoprenoid Biosynthetic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Cellular Ketone Body Metabolic Process Ketone Body Biosynthetic Process
Pathways		Ketone body metabolism PPARA activates gene expression Synthesis of Ketone Bodies Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: APP
Entrez ID		3158
HPRD ID		02580
Ensembl ID		ENSG00000134240
Uniprot IDs		P54868
PDB IDs		2WYA
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth RNA 3'-end Processing Cholesterol Metabolic Process Adult Locomotory Behavior Positive Regulation Of Mitotic Cell Cycle Regulation Of Receptor Activity Cell Recognition
Tagcloud ?		acsm1 apocrine benign carcinomas categorize correspond cysts defining distinctive electable fabp7 golden hmgcr iac iacs identifies melanophilin metaplasia morphological morphologically panel pgdh progesteron proteomics retained signature signatures steroidal transcriptomic