EHD4

Description		EH domain containing 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Early Endosome Endoplasmic Reticulum Plasma Membrane Adherens Junction Membrane Endocytic Vesicle Early Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome Anchoring Junction
	Molecular Function	Nucleotide Binding Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Protein-macromolecule Adaptor Activity Cadherin Binding Metal Ion Binding
	Biological Process	Cell Migration Involved In Sprouting Angiogenesis Endocytosis Pinocytosis Regulation Of Endocytosis Endocytic Recycling Protein Homooligomerization Cilium Assembly Cellular Response To Growth Factor Stimulus Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Granulocyte count ( 27863252) Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte percentage of white cells ( 27863252 32888494) Monocyte count ( 29403010 27863252 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252 32888494) Neutrophil percentage of white cells ( 32888494) Platelet count ( 27863252 32888494) Plateletcrit ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)
Interacting Genes		4 interacting genes: AFP CDC42 RASGRF1 SUMO2
Entrez ID		30844
HPRD ID		10435
Ensembl ID		ENSG00000103966
Uniprot IDs		A8K9B9 Q9H223
PDB IDs
Enriched GO Terms of Interacting Partners?		Progesterone Metabolic Process Sexual Reproduction Ovulation From Ovarian Follicle Small Molecule Binding Ovulation Leading Edge Membrane Positive Regulation Of Pseudopodium Assembly Endothelin Receptor Signaling Pathway Thioesterase Binding Regulation Of Attachment Of Spindle Microtubules To Kinetochore Establishment Of Apical/basal Cell Polarity Neuron Projection Development Positive Regulation Of Pinocytosis Dendritic Cell Migration Apolipoprotein A-I Receptor Binding Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Golgi Localization Establishment Of Monopolar Cell Polarity GTP-dependent Protein Binding Heart Contraction Endothelin Receptor Signaling Pathway Involved In Heart Process Cardiac Conduction System Development Embryonic Heart Tube Development Positive Regulation Of MAPK Cascade Small GTPase-mediated Signal Transduction Neuron Fate Determination Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Dendritic Spine Morphogenesis Establishment Of Golgi Localization Neuron Projection Establishment Of Epithelial Cell Apical/basal Polarity Filopodium Assembly Establishment Or Maintenance Of Monopolar Cell Polarity Neuropilin Signaling Pathway Postsynapse GBD Domain Binding Golgi Transport Complex Storage Vacuole Cell Migration Involved In Heart Development Polarized Epithelial Cell Differentiation Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Glutamate Receptor Binding Positive Regulation Of Rac Protein Signal Transduction Type B Pancreatic Cell Proliferation Positive Regulation Of Ras Protein Signal Transduction SUMO Transferase Activity Protein Tag Activity C21-steroid Hormone Metabolic Process Positive Regulation Of Lamellipodium Assembly
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