HGD

Gene Name		homogentisate 1,2-dioxygenase
Image
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Homogentisate 1,2-dioxygenase Activity Metal Ion Binding
	Biological Process	L-phenylalanine Catabolic Process Tyrosine Catabolic Process Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Phenylalanine and tyrosine catabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: CLDN7 GIT2 PCDHGC3 TERF1
Entrez ID		3081
HPRD ID		06315
Ensembl ID		ENSG00000113924
Uniprot IDs		Q93099
PDB IDs		1EY2 1EYB
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Telomere Maintenance Via Telomere Shortening Negative Regulation Of Telomere Maintenance Via Telomerase Replicative Cell Aging Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Microtubule Polymerization Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules RNA-dependent DNA Replication Behavioral Response To Pain Negative Regulation Of DNA Biosynthetic Process Regulation Of Microtubule Polymerization Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Telomere Maintenance Via Telomere Lengthening Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Response To Pain Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Regulation Of DNA Biosynthetic Process Spindle Checkpoint Negative Regulation Of DNA Replication Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of ARF GTPase Activity Cell Aging Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Cellular Protein Catabolic Process Telomere Maintenance Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Cell Adhesion Negative Regulation Of Chromosome Organization Multicellular Organismal Response To Stress Negative Regulation Of DNA Metabolic Process Regulation Of ARF Protein Signal Transduction
Tagcloud ?		91patients aberrations abnormalities assesses barrett brush carcinogenic combining complementary cytology dysplasia eac esophagus evaluates fish goes gold histopathological ihc inc indirectly lgd periodicals representative respect staging tp53 unreliable wiley