HELLS

Gene Name		helicase, lymphoid-specific
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Nucleus Pericentric Heterochromatin
	Molecular Function	DNA Binding Helicase Activity Protein Binding ATP Binding
	Biological Process	Methylation-dependent Chromatin Silencing Transcription, DNA-templated Mitotic Nuclear Division Multicellular Organismal Development Maintenance Of DNA Methylation Pericentric Heterochromatin Assembly Lymphocyte Proliferation Cell Division
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: APP DNMT1 DNMT3B E2F3 HDAC1
Entrez ID		3070
HPRD ID		07232
Ensembl ID		ENSG00000119969
Uniprot IDs		Q9NRZ9
PDB IDs
Enriched GO Terms of Interacting Partners?		C-5 Methylation Of Cytosine Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Gene Expression DNA Methylation On Cytosine Notch Signaling Pathway Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K4 Methylation Negative Regulation Of Histone Methylation Regulation Of Gene Expression, Epigenetic Regulation Of Histone H3-K4 Methylation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Histone Methylation Regulation Of Histone Methylation DNA Methylation Cellular Response To Amino Acid Stimulus Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Histone Modification DNA Modification Negative Regulation Of Chromosome Organization Chromatin Modification Regulation Of Transcription From RNA Polymerase II Promoter Gene Silencing Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Response To Amino Acid Regulation Of RNA Metabolic Process Chromatin Organization Regulation Of Histone Modification Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Gene Expression Synaptic Growth At Neuromuscular Junction Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Protein Metabolic Process Cellular Response To Acid Chemical Collateral Sprouting In Absence Of Injury S-adenosylmethioninamine Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Chromosome Organization Chromosome Organization DNA Methylation On Cytosine Within A CG Sequence DNA-templated Transcription, Initiation
Tagcloud ?		arrays atherosclerosis cpg cytosine dnmt1 e1 epigenetic fli1 friend hcys helicase homocysteine immunoblots integration janus linking lox lymphoid lysyl mc3t3 methyltransferases osteoblastic osteoblasts osteoclasts oxidase pathologies repressing repressive revealing