NOP53

Description		NOP53 ribosome biogenesis factor
Image
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytosol RDNA Heterochromatin
	Molecular Function	P53 Binding RNA Binding Protein Binding 5S RRNA Binding Identical Protein Binding
	Biological Process	Ribosomal Large Subunit Assembly Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Protein Phosphorylation DNA Repair RRNA Processing DNA Damage Response Mitotic G2 DNA Damage Checkpoint Signaling Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of RIG-I Signaling Pathway Ribosome Biogenesis Regulation Of Apoptotic Process Protein Stabilization Regulation Of Cell Cycle Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Response To Hypoxia Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Protein Localization To Nucleolus Positive Regulation Of Protein K63-linked Deubiquitination Regulation Of Aerobic Respiration Protein Localization To Nucleoplasm
Pathways
Drugs
Diseases
GWAS
Interacting Genes		15 interacting genes: CCDC136 CDKN2A CEP70 CFTR GRSF1 HAP1 HMGB2 OGT PPP1CA PSMA1 SPTBN1 SRPK2 TP53 TSPYL2 UPF2
Entrez ID		29997
HPRD ID		16142
Ensembl ID		ENSG00000105373
Uniprot IDs		Q9NZM5
PDB IDs		8FKZ 8FL2 8FL3 8FL4 8FL6 8FL7 8FLA 8FLB 8FLD 8FLE 8INE 8INF 8IPX 8IPY 8IR3
Enriched GO Terms of Interacting Partners?		Nucleolus 14-3-3 Protein Binding Autophagy Of Mitochondrion Protein-containing Complex Cytoplasm Regulation Of Carbohydrate Catabolic Process Regulation Of Cellular Localization Nucleus Organization Organelle Organization MDM2/MDM4 Family Protein Binding Replicative Senescence Developmental Process Regulation Of Glucose Metabolic Process Nuclear Body Organization Autophagy RRNA Transcription Entrainment Of Circadian Clock By Photoperiod Regulation Of Generation Of Precursor Metabolites And Energy Circadian Rhythm Negative Regulation Of DNA Replication Disordered Domain Specific Binding Negative Regulation Of Proteolysis Photoperiodism Entrainment Of Circadian Clock Positive Regulation Of Leukocyte Apoptotic Process Positive Regulation Of Gene Expression Cellular Component Assembly Negative Regulation Of Cell Growth Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Cellular Component Organization Anatomical Structure Formation Involved In Morphogenesis Regulation Of Programmed Necrotic Cell Death Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Transporter Activity Chromatin Organization Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Oxygen-containing Compound Negative Regulation Of Growth Nucleic Acid Metabolic Process RNA Metabolic Process Ligase Inhibitor Activity Regulation Of Cell Communication Nucleus Regulation Of Signaling Catabolic Process Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Double-strand Break Repair Negative Regulation Of Helicase Activity
Tagcloud ?