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GTF2H3
Gene Name
general transcription factor IIH, polypeptide 3, 34kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Core TFIIH Complex
Nucleoplasm
Holo TFIIH Complex
Molecular Function
Damaged DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Kinase Activity
DNA-dependent ATPase Activity
Translation Factor Activity, Nucleic Acid Binding
RNA Polymerase II Carboxy-terminal Domain Kinase Activity
Metal Ion Binding
Protein N-terminus Binding
Biological Process
Nucleotide-excision Repair, DNA Damage Removal
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Translation
Protein Phosphorylation
Gene Expression
Viral Process
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Viral Transcription
Pathways
RNA Polymerase II Promoter Escape
Formation of HIV-1 elongation complex containing HIV-1 Tat
Nucleotide Excision Repair
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Clearance
HIV Infection
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Formation of transcription-coupled NER (TC-NER) repair complex
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
Dual incision reaction in TC-NER
NoRC negatively regulates rRNA expression
HIV Transcription Initiation
HIV Life Cycle
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
Dual incision reaction in GG-NER
mRNA Capping
RNA Polymerase I Transcription
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
Global Genomic NER (GG-NER)
RNA Polymerase II Transcription Initiation And Promoter Clearance
Transcription-coupled NER (TC-NER)
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
Formation of incision complex in GG-NER
RNA Polymerase II Transcription Initiation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-protein Interactions
9 interactors:
AR
CDK7
ERCC2
ERCC3
GTF2H1
GTF2H2
GTF2H2C_2
GTF2H4
XBP1P1
Entrez ID
2967
HPRD ID
07531
Ensembl ID
ENSG00000111358
Uniprot IDs
B4DNZ6
Q13889
PDB IDs
Enriched GO Terms of Interacting Partners
?
Nucleotide-excision Repair, DNA Damage Removal
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Nucleotide-excision Repair
7-methylguanosine MRNA Capping
Transcription From RNA Polymerase I Promoter
7-methylguanosine RNA Capping
Transcription-coupled Nucleotide-excision Repair
Positive Regulation Of Viral Transcription
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Regulation Of Viral Transcription
Positive Regulation Of Viral Process
DNA-templated Transcription, Termination
Negative Regulation Of Gene Expression, Epigenetic
DNA-templated Transcription, Elongation
DNA-templated Transcription, Initiation
DNA Catabolic Process
Regulation Of Viral Process
Regulation Of Gene Expression, Epigenetic
DNA Repair
Cellular Response To DNA Damage Stimulus
Transcription From RNA Polymerase II Promoter
MRNA Processing
Aromatic Compound Catabolic Process
DNA Metabolic Process
MRNA Metabolic Process
Viral Process
RNA Processing
Transcription, DNA-templated
RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Response To Stress
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Cellular Macromolecule Catabolic Process
RNA Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Protein Phosphorylation
Negative Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
DNA Duplex Unwinding
DNA Geometric Change
Regulation Of RNA Metabolic Process
Tagcloud
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chek2
clk2
comprehensively
escc
esophageal
fance
fen1
gc
genetics
genotyped
germline
han
hel308
linxian
mpg
mre11a
pole
polq
propensity
rad54b
rad54l
resampling
shanxi
smug1
snps
sum
tdg
validate
warranted