GSTM2

Description		glutathione S-transferase mu 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Sarcoplasmic Reticulum Extracellular Exosome
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Fatty Acid Binding Protein Binding Transferase Activity Calcium Channel Inhibitor Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Glutathione Binding Transmembrane Transporter Binding
	Biological Process	Lipid Metabolic Process Glutathione Metabolic Process Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Nitrobenzene Metabolic Process Xenobiotic Catabolic Process Linoleic Acid Metabolic Process Hepoxilin Biosynthetic Process Relaxation Of Cardiac Muscle Cellular Detoxification Of Nitrogen Compound Cellular Response To Caffeine Cellular Oxidant Detoxification
Pathways		Glutathione conjugation
Drugs		Glutathione S-(2,4-dinitrophenyl)glutathione Glutathione disulfide Glutathione disulfide Deoxycholic acid S-Methyl glutathione
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) HDL cholesterol levels ( 32203549) LDL cholesterol levels ( 32203549) Metabolite levels ( 31628463) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		3 interacting genes: GSTM1 GSTM3 PTEN
Entrez ID		2946
HPRD ID		00710
Ensembl ID		ENSG00000213366
Uniprot IDs		P28161 Q0D2I8
PDB IDs		1HNA 1HNB 1HNC 1XW5 1YKC 2AB6 2C4J 2GTU 3GTU 3GUR 5HWL
Enriched GO Terms of Interacting Partners?		Nitrobenzene Metabolic Process Detoxification Of Nitrogen Compound Cellular Detoxification Of Nitrogen Compound Glutathione Binding Benzene-containing Compound Metabolic Process Glutathione Transferase Activity Xenobiotic Catabolic Process Enzyme Binding Glutathione Metabolic Process Xenobiotic Metabolic Process Cellular Detoxification Negative Regulation Of Synaptic Vesicle Clustering Modified Amino Acid Metabolic Process Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Establishment Of Blood-nerve Barrier Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Sulfur Compound Metabolic Process Glutathione Derivative Biosynthetic Process Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Identical Protein Binding Hepoxilin Biosynthetic Process Sperm Fibrous Sheath Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering Postsynaptic Density Assembly Neuron-neuron Synaptic Transmission Negative Regulation Of Cell Size Anaphase-promoting Complex Binding Forebrain Morphogenesis Presynaptic Membrane Assembly Presynaptic Membrane Organization Postsynaptic Specialization Assembly Schmidt-Lanterman Incisure Negative Regulation Of Excitatory Postsynaptic Potential Locomotor Rhythm Cellular Response To Electrical Stimulus Ubiquitin Ligase Activator Activity Spindle Assembly Involved In Female Meiosis Maternal Behavior Phosphatidylinositol-3-phosphate Phosphatase Activity Prepulse Inhibition Meiotic Spindle Assembly Myelin Maintenance
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