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GSTM2
Gene Name
glutathione S-transferase mu 2 (muscle)
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Sarcoplasmic Reticulum
Extracellular Vesicular Exosome
Molecular Function
Glutathione Transferase Activity
Receptor Binding
Enzyme Binding
Protein Homodimerization Activity
Glutathione Binding
Biological Process
Glutathione Metabolic Process
Xenobiotic Metabolic Process
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion
Nitrobenzene Metabolic Process
Xenobiotic Catabolic Process
Small Molecule Metabolic Process
Relaxation Of Cardiac Muscle
Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Cellular Detoxification Of Nitrogen Compound
Cellular Response To Caffeine
Glutathione Derivative Biosynthetic Process
Pathways
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
Defective UGT1A4 causes hyperbilirubinemia
Glutathione conjugation
Metabolic disorders of biological oxidation enzymes
Phase II conjugation
Defective UGT1A1 causes hyperbilirubinemia
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
Biological oxidations
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
Defective GGT1 causes Glutathionuria (GLUTH)
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Glutathione
Glutathione S-(2,4 Dinitrobenzene)
Oxidized Glutathione Disulfide
S-METHYL-GLUTATHIONE
Diseases
GWAS
Protein-protein Interactions
2 interactors:
GSTM1
GSTM3
Entrez ID
2946
HPRD ID
00710
Ensembl ID
ENSG00000213366
Uniprot IDs
P28161
Q0D2I8
PDB IDs
1HNA
1HNB
1HNC
1XW5
1YKC
2AB6
2C4J
2GTU
3GTU
3GUR
Enriched GO Terms of Interacting Partners
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Cellular Detoxification Of Nitrogen Compound
Nitrobenzene Metabolic Process
Detoxification Of Nitrogen Compound
Xenobiotic Catabolic Process
Glutathione Derivative Biosynthetic Process
Glutathione Metabolic Process
Xenobiotic Metabolic Process
Cellular Response To Xenobiotic Stimulus
Response To Xenobiotic Stimulus
Peptide Metabolic Process
Response To Toxic Substance
Cellular Modified Amino Acid Metabolic Process
Cellular Amide Metabolic Process
Sulfur Compound Metabolic Process
Establishment Of Blood-nerve Barrier
Endothelial Cell Development
Cellular Response To Stress
Catabolic Process
Endothelial Cell Differentiation
Endothelium Development
Peripheral Nervous System Development
Small Molecule Metabolic Process
Epithelial Cell Development
Response To Estrogen
Response To Stress
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