PRSS50

Description		serine protease 50
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum
	Molecular Function	Serine-type Endopeptidase Activity Threonine-type Endopeptidase Activity Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis
Pathways
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653)
Novel Interacting Genes		1 novel interacting genes: CCR1
Interacting Genes		7 interacting genes: ACVR2A CASP8 ESR2 HRAS STK11 TGFB1 TSG101
Entrez ID		29122
HPRD ID		06405
Ensembl ID		ENSG00000283706
Uniprot IDs		A0A140VJY3 Q9UI38
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Myeloid Cell Differentiation Negative Regulation Of Ossification Regulation Of Myeloid Cell Differentiation Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Ossification Positive Regulation Of Signal Transduction Regulation Of Cell Development Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Cell Differentiation Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Immune System Process Response To Estradiol Apoptotic Signaling Pathway Regulation Of Cell Growth Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Macrophage Differentiation Regulation Of Hemopoiesis Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Cell Development Response To Ionizing Radiation Regulation Of Signal Transduction Positive Regulation Of Immune System Process Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of Macrophage Differentiation Positive Regulation Of Inflammatory Response Negative Regulation Of Cell Growth Cellular Response To Radiation Epithelial Cell Proliferation Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Migration Negative Regulation Of Biomineral Tissue Development Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Leukocyte Differentiation Positive Regulation Of Cell Motility Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Locomotion Regulation Of Growth Regulation Of Macromolecule Metabolic Process Negative Regulation Of Growth Positive Regulation Of Developmental Process Positive Regulation Of SMAD Protein Signal Transduction Regulation Of Multicellular Organismal Development Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Regulation Of ERK1 And ERK2 Cascade
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