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ORMDL2

Name ORMDL sphingolipid biosynthesis regulator 2
Structure No pdb structure
Novel Interactors 1 novel interactors: RNF41
Interactors 27 interactors: AQP6 BIK CD79A CREB3L1 CYB561 CYB5R3 DAPK1 EBP ELOVL4 ERGIC3 FAM210B FCER1G GJA8 KCNJ6 MMGT1 MTIF3 RETREG3 SAR1A SCN3B SLC10A1 SLC35H1 TIMMDC1 TMEM120A TMEM31 TMEM86B TMX2 ZDHHC15
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Membrane
  • Serine Palmitoyltransferase Complex
Molecular Function
  • Protein Binding
Biological Process
  • Sphingolipid Metabolic Process
  • Ceramide Metabolic Process
  • Sphingolipid Biosynthetic Process
  • Intracellular Sphingolipid Homeostasis
  • Negative Regulation Of Ceramide Biosynthetic Process
  • Regulation Of Ceramide Biosynthetic Process
Pathways
  • Sphingolipid de novo biosynthesis
GWAS
  • Refractive error ( 32231278 )
Entrez ID 29095
HPRD ID 17802
Ensembl ID ENSG00000123353
Uniprot IDs Q53FV1
PDB IDs Not available
GO Terms Enriched among Interactors ?
  • Membrane
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane

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