ARHGAP35

Gene Name		Rho GTPase activating protein 35
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Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Actin Cytoskeleton
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Transcription Corepressor Activity Rho GTPase Activator Activity GTP Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Neural Tube Closure Transcription, DNA-templated Small GTPase Mediated Signal Transduction Axon Guidance Regulation Of Cell Shape Positive Regulation Of Neuron Projection Development Forebrain Development Positive Regulation Of Rho GTPase Activity Negative Regulation Of Rho Protein Signal Transduction Camera-type Eye Development Negative Regulation Of Vascular Permeability Negative Regulation Of Transcription, DNA-templated Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle Axon guidance Semaphorin interactions Signaling by Rho GTPases Sema4D mediated inhibition of cell attachment and migration Sema4D in semaphorin signaling
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: HDAC1 KRT31 PTPRZ1 RHOA SRC
Entrez ID		2909
HPRD ID		05592
Ensembl ID		ENSG00000160007
Uniprot IDs		Q9NRY4
PDB IDs		2K85 3C5H 3FK2
Enriched GO Terms of Interacting Partners?		Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Epithelium Development Blood Coagulation Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Hemostasis Regulation Of Cell Proliferation Axonogenesis Viral Process Axon Development Tissue Development Regulation Of Body Fluid Levels Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Wound Healing Response To Growth Factor Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Neuron Projection Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Wounding Cell Morphogenesis Involved In Differentiation Neuron Projection Development Anatomical Structure Development Cellular Response To Progesterone Stimulus Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Anatomical Structure Morphogenesis Regulation Of Cell Cycle Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Skeletal Muscle Satellite Cell Migration Neuron Development Platelet Activation Central Nervous System Development Developmental Process Cell-cell Junction Organization Cell Morphogenesis Ras Protein Signal Transduction Bone Development Positive Regulation Of Integrin Activation Positive Regulation Of Podosome Assembly Negative Regulation Of Mitochondrial Depolarization Neuron Differentiation Cell Projection Organization Organ Development
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