FLVCR1

Description		FLVCR choline and heme transporter 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Choline Transmembrane Transporter Activity Heme Transmembrane Transporter Activity Heme Binding Transmembrane Transporter Activity Ethanolamine Transmembrane Transporter Activity
	Biological Process	Blood Vessel Development In Utero Embryonic Development Heme Biosynthetic Process Mitochondrial Transport Intracellular Iron Ion Homeostasis Phospholipid Biosynthetic Process Choline Transport Heme Transport Erythrocyte Differentiation Ethanolamine Transport Limb Morphogenesis Multicellular Organism Growth Embryonic Digit Morphogenesis Erythrocyte Maturation Regulation Of Organ Growth Spleen Development Embryonic Skeletal System Morphogenesis Transmembrane Transport Head Morphogenesis Heme Export
Pathways
Drugs
Diseases		Posterior column ataxia with retinitis pigmentosa (PCARP)
GWAS		Asthma (childhood onset) ( 30929738) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494)
Novel Interacting Genes		1 novel interacting genes: NEK2
Interacting Genes
Entrez ID		28982
HPRD ID		16451
Ensembl ID		ENSG00000162769
Uniprot IDs		B2RB38 Q9Y5Y0
PDB IDs		8QCS 8QCT 8R8T 8UBW 8UBX 8UBY 8UBZ 8UC0
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Centriole-centriole Cohesion Regulation Of Centriole-centriole Cohesion Regulation Of Mitotic Centrosome Separation Centrosome Separation Condensed Chromosome Regulation Of Attachment Of Spindle Microtubules To Kinetochore Mitotic Sister Chromatid Segregation Nuclear Lumen Blastocyst Development Condensed Nuclear Chromosome Nuclear Chromosome Segregation Sister Chromatid Segregation Mitotic Spindle Assembly Positive Regulation Of Telomere Maintenance Protein Phosphatase Binding Mitotic Spindle Organization Spindle Assembly Intercellular Bridge Meiotic Cell Cycle Spindle Organization Chromosome, Centromeric Region Chromosome Segregation Protein Autophosphorylation Positive Regulation Of Chromosome Organization Regulation Of Nuclear Division Regulation Of Mitotic Nuclear Division Spindle Pole Regulation Of Telomere Maintenance Microtubule Cytoskeleton Organization Involved In Mitosis Mitotic Cell Cycle Kinetochore Midbody Microtubule Cytoskeleton Regulation Of Chromosome Organization Negative Regulation Of Cell Cycle Process Positive Regulation Of DNA Metabolic Process Membraneless Organelle Assembly
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