LIN9

Description		lin-9 DREAM MuvB core complex component
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Repressor Complex
	Molecular Function	DNA Binding Protein Binding
	Biological Process	DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle DNA Biosynthetic Process
Pathways		Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 G0 and Early G1 Polo-like kinase mediated events Cyclin E associated events during G1/S transition G1/S-Specific Transcription Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases
GWAS		Caudate nucleus volume ( 31530798) Gut microbiota beta diversity (weighted UniFrac distance) ( 33208821) Heel bone mineral density x serum urate levels interaction ( 34046847) Mean corpuscular hemoglobin ( 32888494) Mean platelet volume ( 32888494) Nicotine dependence symptom count ( 25555482)
Interacting Genes		3 interacting genes: MYBL2 RB1 RBBP4
Entrez ID		286826
HPRD ID		13990
Ensembl ID		ENSG00000183814
Uniprot IDs		H0Y322 Q5TKA1 Q6P142
PDB IDs		6C48 7N40 7R1D
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Myb Complex Negative Regulation Of Myofibroblast Differentiation Sister Chromatid Biorientation Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Lipid Kinase Activity Negative Regulation Of Hepatocyte Apoptotic Process Enucleate Erythrocyte Differentiation Glial Cell Apoptotic Process Rb-E2F Complex Regulation Of Centromere Complex Assembly Chromatin Lock Complex Positive Regulation Of Collagen Fibril Organization CAF-1 Complex DNA Replication-dependent Chromatin Assembly NURF Complex Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Myofibroblast Differentiation Regulation Of Collagen Fibril Organization Cyclin/CDK Positive Transcription Elongation Factor Complex Importin-alpha Family Protein Binding Positive Regulation Of Transcription Regulatory Region DNA Binding ATPase Complex Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macrophage Differentiation Positive Regulation Of Mitotic Metaphase/anaphase Transition Hepatocyte Apoptotic Process Regulation Of Transcription Regulatory Region DNA Binding Negative Regulation Of Glial Cell Proliferation ESC/E(Z) Complex NuRD Complex Positive Regulation Of Biosynthetic Process Positive Regulation Of Mitotic Sister Chromatid Separation Positive Regulation Of DNA Binding Cell Morphogenesis Involved In Neuron Differentiation Sin3-type Complex Regulation Of Cell Fate Specification Chromatin Remodeling Regulation Of Macrophage Differentiation Negative Regulation Of Stem Cell Population Maintenance Disordered Domain Specific Binding Positive Regulation Of Extracellular Matrix Organization Negative Regulation Of Epithelial Cell Apoptotic Process Glial Cell Proliferation Negative Regulation Of Cell Population Proliferation Neuron Maturation SWI/SNF Complex
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