GPR39

Gene Name		G protein-coupled receptor 39
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	G-protein Coupled Receptor Activity Metal Ion Binding
	Biological Process	G-protein Coupled Receptor Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Hypertension ( 21626137)
Protein-protein Interactions		1 interactors: GSK3B
Entrez ID		2863
HPRD ID		04198
Ensembl ID		ENSG00000183840
Uniprot IDs		O43194
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Hypermethylation Of CpG Island Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Cellular Response To Interleukin-3 Regulation Of Neuron Maturation Negative Regulation Of Glycogen (starch) Synthase Activity Protein Localization To Microtubule Negative Regulation Of Dendrite Morphogenesis Negative Regulation Of NFAT Protein Import Into Nucleus ER Overload Response Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Muscle Hypertrophy Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Protein Export From Nucleus Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Dendrite Development Regulation Of DNA Methylation Myoblast Fusion Protein Localization To Cytoskeleton Regulation Of Gene Expression By Genetic Imprinting Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Response To Lithium Ion Regulation Of Cellular Response To Heat Regulation Of Cardiac Muscle Hypertrophy Regulation Of Protein Export From Nucleus Regulation Of Glycogen Biosynthetic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Syncytium Formation Genetic Imprinting Negative Regulation Of Epithelial Cell Differentiation Protein Export From Nucleus Regulation Of Glycogen Metabolic Process Positive Regulation Of Axon Extension Negative Regulation Of Transcription Factor Import Into Nucleus Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Stem Cell Differentiation Positive Regulation Of Cell-matrix Adhesion Negative Regulation Of Protein Binding Epithelial To Mesenchymal Transition Positive Regulation Of Rac GTPase Activity Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Mitochondrion Organization Myotube Differentiation Glycogen Metabolic Process Cellular Response To Heat
Tagcloud ?		adrenal antidepressant anxiety axis bdnf cortex corticosterone creb dark depressive forced frontal glucocorticoid hippocampus hypothalamus immobility knockout metabotropic neurotransmitter neurotrophic pituitary sensing suspension swim tail trkb tropomyosin zinc zn2