GPR39

Description		G protein-coupled receptor 39
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Metal Ion Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways		Class A/1 (Rhodopsin-like receptors) G alpha (q) signalling events G alpha (s) signalling events
Drugs
Diseases
GWAS		Calcium levels ( 25972035) Post bronchodilator FEV1/FVC ratio in smoking ( 30068317) Post bronchodilator percent predicted FEV1 in smoking ( 30068317)
Interacting Genes		1 interacting genes: GSK3B
Entrez ID		2863
HPRD ID		04198
Ensembl ID		ENSG00000183840
Uniprot IDs		O43194
PDB IDs
Enriched GO Terms of Interacting Partners?		Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Microtubule Anchoring At Centrosome TORC2 Signaling Negative Regulation Of Calcineurin-NFAT Signaling Cascade Beta-catenin Destruction Complex Negative Regulation Of Glycogen Biosynthetic Process Wnt Signalosome ER Overload Response Regulation Of Protein Localization To Cilium Regulation Of Dopaminergic Neuron Differentiation Regulation Of Type B Pancreatic Cell Development Regulation Of Protein Localization To Centrosome Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Protein Localization To Cilium Regulation Of Cellular Response To Heat Positive Regulation Of Protein Binding Negative Regulation Of TORC2 Signaling Maintenance Of Cell Polarity Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Dopaminergic Neuron Differentiation Regulation Of TORC2 Signaling Cellular Response To Interleukin-3 Regulation Of Glycogen (starch) Synthase Activity Protein Kinase A Catalytic Subunit Binding Dynactin Binding Positive Regulation Of Protein Localization To Centrosome Negative Regulation Of Calcium-mediated Signaling Tau-protein Kinase Activity Positive Regulation Of Protein Export From Nucleus Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Heart Valve Development Negative Regulation Of Stem Cell Differentiation Viral Protein Processing Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand ER-nucleus Signaling Pathway Regulation Of Protein Export From Nucleus Regulation Of Calcineurin-mediated Signaling Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Cilium Assembly NF-kappaB Binding Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Membrane Permeability Cytoplasmic Translational Initiation Negative Regulation Of Protein Localization To Nucleus
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