PAXX

Description		PAXX non-homologous end joining factor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytoplasm Site Of Double-strand Break Ku70:Ku80 Complex Nonhomologous End Joining Complex
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity Molecular Adaptor Activity DNA Polymerase Binding
	Biological Process	DNA Repair Double-strand Break Repair Via Nonhomologous End Joining DNA Damage Response
Pathways
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: APP CDC42
Entrez ID		286257
HPRD ID		14163
Ensembl ID		ENSG00000310560
Uniprot IDs		Q9BUH6
PDB IDs		3WTD 3WTF 4WJA 7ZWA 7ZYG 8ASC 8BH3 8BHV 8BHY 8EZA 8EZB
Enriched GO Terms of Interacting Partners?		Neuron Projection Organization Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Cell Projection Morphogenesis Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Postsynapse Regulation Of Synapse Organization Cytoskeleton-dependent Intracellular Transport Regulation Of Response To Calcium Ion Microtubule-based Transport Transport Along Microtubule Amylin Binding Neuron Projection Morphogenesis Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Endothelin Production Positive Regulation Of Endocytosis Growth Cone Filopodium Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Postsynapse Organization Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Endocytosis Endothelin Receptor Signaling Pathway Involved In Heart Process GBD Domain Binding Storage Vacuole Positive Regulation Of Cell Cycle Neuron Projection Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Regulation Of Supramolecular Fiber Organization Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Microtubule-based Movement
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