SH3PXD2B

Gene Name		SH3 and PX domains 2B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Podosome Cytoplasm Cell Junction Cell Projection
	Molecular Function	Protein Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding SH2 Domain Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Skeletal System Development Eye Development Superoxide Metabolic Process Heart Development Extracellular Matrix Disassembly Cell Differentiation Positive Regulation Of Fat Cell Differentiation Bone Development Adipose Tissue Development Podosome Assembly Protein Localization To Membrane
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: FASLG
Entrez ID		285590
HPRD ID		18591
Ensembl ID		ENSG00000174705
Uniprot IDs		A1X283 G3V144
PDB IDs
Enriched GO Terms of Interacting Partners?		Endosomal Lumen Acidification Retinal Cell Programmed Cell Death Necroptotic Signaling Pathway Cellular Chloride Ion Homeostasis Inflammatory Cell Apoptotic Process Chloride Ion Homeostasis Positive Regulation Of Endothelial Cell Apoptotic Process T Cell Apoptotic Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Intracellular PH Reduction PH Reduction Positive Regulation Of ERBB Signaling Pathway Endosome Organization Necroptotic Process Regulation Of Endothelial Cell Apoptotic Process Developmental Programmed Cell Death Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Intracellular PH Programmed Necrotic Cell Death Anion Homeostasis Regulation Of Cellular PH Necrotic Cell Death Positive Regulation Of Neuron Apoptotic Process Regulation Of PH Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Death Regulation Of ERBB Signaling Pathway Negative Regulation Of Angiogenesis Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Extrinsic Apoptotic Signaling Pathway Zymogen Activation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Positive Regulation Of Peptidase Activity Eye Morphogenesis Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Angiogenesis Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Processing Regulation Of Neuron Apoptotic Process Regulation Of Neuron Death Positive Regulation Of Proteolysis Response To Lipopolysaccharide Response To Molecule Of Bacterial Origin
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