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MCHR1
Gene Name
melanin-concentrating hormone receptor 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Nonmotile Primary Cilium
Ciliary Membrane
Molecular Function
G-protein Coupled Receptor Activity
Protein C-terminus Binding
Neuropeptide Receptor Activity
Melanin-concentrating Hormone Receptor Activity
Hormone Binding
Biological Process
Generation Of Precursor Metabolites And Energy
G-protein Coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Neuropeptide Signaling Pathway
Feeding Behavior
Positive Regulation Of Calcium Ion Transport
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
G alpha (q) signalling events
Signaling by GPCR
Cargo trafficking to the periciliary membrane
Organelle biogenesis and maintenance
Class A/1 (Rhodopsin-like receptors)
Assembly of the primary cilium
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
BBSome-mediated cargo-targeting to cilium
G alpha (q) signalling events
GPCR downstream signaling
Peptide ligand-binding receptors
Gastrin-CREB signalling pathway via PKC and MAPK
G alpha (i) signalling events
Drugs
Diseases
GWAS
Protein-protein Interactions
2 interactors:
PMCH
ZMYND19
Entrez ID
2847
HPRD ID
11874
Ensembl ID
ENSG00000128285
Uniprot IDs
A6ZJ87
Q5IFI4
Q99705
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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ac3
adenylyl
alms1
alstrom
anomalies
antennae
appetite
arl13b
bardet
bbs
biedl
cilia
ciliary
ciliopathies
ciliopathy
coinciding
develops
displaying
etiologies
foz
hyperphagia
localizes
maintains
morbid
organelle
parallels
satiety
sstr3
truncating