PTGR3

Description		prostaglandin reductase 3
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GO Annotations	Cellular Component	Mitochondrion Peroxisome
	Molecular Function	Zinc Ion Binding Oxidoreductase Activity 15-oxoprostaglandin 13-reductase [NAD(P)+] Activity
	Biological Process	Lipid Metabolic Process Prostaglandin Metabolic Process Negative Regulation Of Fat Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: APP LNX1 NEDD4L
Entrez ID		284273
HPRD ID		15685
Ensembl ID		ENSG00000180011
Uniprot IDs		Q4G1C4 Q8N4Q0
PDB IDs		2C0C 2WEK 2X1H 2X7H 7ZEJ
Enriched GO Terms of Interacting Partners?		Synapse Organization Cell Junction Organization Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Postsynapse Regulation Of Response To Calcium Ion Developmental Maturation Amylin Binding Positive Regulation Of Protein Catabolic Process Endosome To Plasma Membrane Transport Vesicle Negative Regulation Of Protein Localization Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Positive Regulation Of Endocytosis Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Monoatomic Cation Transmembrane Transport Negative Regulation Of Sodium Ion Import Across Plasma Membrane Positive Regulation Of Caveolin-mediated Endocytosis Ubiquitin-protein Transferase Activity Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Regulation Of Monoatomic Ion Transmembrane Transport Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission Regulation Of Synapse Organization Regulation Of Developmental Growth NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Regulation Of Endocytosis Negative Regulation Of Potassium Ion Export Across Plasma Membrane Axon Choice Point Recognition Regulation Of Metal Ion Transport Regulation Of Caveolin-mediated Endocytosis
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