NUDT7

Description		nudix hydrolase 7
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GO Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol
	Molecular Function	Magnesium Ion Binding RNA Binding Coenzyme A Diphosphatase Activity Hydrolase Activity Hydrolase Activity, Acting On Acid Anhydrides, In Phosphorus-containing Anhydrides Manganese Ion Binding SnoRNA Binding Metal Ion Binding 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] Hydrolase Activity
	Biological Process	Nucleoside Diphosphate Metabolic Process Coenzyme A Catabolic Process Medium-chain Fatty-acyl-CoA Catabolic Process Butyryl-CoA Catabolic Process Acetyl-CoA Catabolic Process Brown Fat Cell Differentiation Succinyl-CoA Catabolic Process Propionyl-CoA Metabolic Process Propionyl-CoA Catabolic Process Malonyl-CoA Catabolic Process
Pathways		Peroxisomal lipid metabolism Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Glaucoma (primary open-angle) ( 33627673) Graft survival time in renal transplantation (donor effect) ( 32080893) Intraocular pressure ( 29235454 29617998) Obesity-related traits ( 23251661)
Interacting Genes		1 interacting genes: PEX5
Entrez ID		283927
HPRD ID		19532
Ensembl ID		ENSG00000140876
Uniprot IDs		A0A087WVP7 P0C024
PDB IDs		5QGG 5QGH 5QGI 5QGJ 5QGK 5QGL 5QGM 5QGN 5QGO 5QGP 5QGQ 5QGR 5QGS 5QGT 5QGU 5QGV 5QGW 5QGX 5QGY 5QGZ 5QH0 5QH1 5QH2 5QH3 5QH4 5QH5 5QH6 5QH7 5QH8 5QH9 5QHA 5QHB 5QHC 5QHE 5QHF 5QHG 5QHH 5T3P
Enriched GO Terms of Interacting Partners?		Protein Import Into Peroxisome Matrix, Translocation Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Peroxisome Targeting Sequence Binding Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Membrane Protein Import Into Peroxisome Matrix, Substrate Release Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Carrier Chaperone Protein Unfolding Protein Import Into Peroxisome Matrix Pexophagy Peroxisomal Membrane Transport Establishment Of Protein Localization To Peroxisome Cerebral Cortex Neuron Differentiation Receptor Recycling Peroxisome Organization Intracellular Protein Transmembrane Transport Cerebral Cortex Cell Migration Positive Regulation Of Multicellular Organism Growth Very Long-chain Fatty Acid Metabolic Process Forebrain Neuron Differentiation Telencephalon Cell Migration Forebrain Cell Migration Receptor Metabolic Process Peroxisomal Matrix Fatty Acid Beta-oxidation Protein Monoubiquitination Endoplasmic Reticulum Organization Peroxisomal Membrane Regulation Of Multicellular Organism Growth Protein Transmembrane Transport Fatty Acid Oxidation Fatty Acid Catabolic Process Lipid Oxidation Protein Tetramerization Cellular Response To Reactive Oxygen Species Neuromuscular Process Mitochondrial Membrane Organization Peroxisome Lipid Modification Central Nervous System Neuron Differentiation Protein-containing Complex Disassembly Negative Regulation Of Protein-containing Complex Assembly Neuron Migration Macroautophagy Positive Regulation Of Developmental Growth Response To Reactive Oxygen Species Establishment Of Protein Localization To Membrane
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