GPR15

Description		G protein-coupled receptor 15
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GO Annotations	Cellular Component	Cytoplasm Endosome Plasma Membrane Membrane
	Molecular Function	Virus Receptor Activity G Protein-coupled Receptor Activity Protein Binding Coreceptor Activity
	Biological Process	Angiogenesis Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Symbiont Entry Into Host Cell T Cell Migration
Pathways		G alpha (s) signalling events
Drugs
Diseases
GWAS		Circulating leptin levels in high cardiovascular risk ( 31766143)
Novel Interacting Genes		1 novel interacting genes: FER
Interacting Genes		1 interacting genes: APP
Entrez ID		2838
HPRD ID		03102
Ensembl ID		ENSG00000154165
Uniprot IDs		B2R8H6 B6V9G9 P49685
PDB IDs		8ZQE
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Response To Growth Factor Amylin Binding Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Endosome To Plasma Membrane Transport Vesicle Chemotaxis Regulation Of Supramolecular Fiber Organization Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Locomotion Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Cellular Response To Macrophage Colony-stimulating Factor Stimulus Negative Regulation Of Mast Cell Activation Involved In Immune Response Cell-cell Junction Disassembly Adherens Junction Disassembly Tyrosine Phosphorylation Of STAT Protein Extracellular Matrix-cell Signaling Kit Signaling Pathway Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Cell Junction Organization Axon Choice Point Recognition Diapedesis Heparan Sulfate Binding Signaling Receptor Activator Activity
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