SLC24A5

Description		solute carrier family 24 member 5
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Membrane Trans-Golgi Network Membrane Melanosome
	Molecular Function	Calcium Channel Activity Protein Binding Calcium, Potassium:sodium Antiporter Activity Calcium Ion Transmembrane Transporter Activity Symporter Activity Antiporter Activity
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Calcium Ion Transport Intracellular Calcium Ion Homeostasis Monoatomic Ion Transmembrane Transport Sodium Ion Transmembrane Transport Melanin Biosynthetic Process Negative Regulation Of Melanin Biosynthetic Process Transmembrane Transport Calcium Ion Import Calcium Ion Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways		Sodium/Calcium exchangers Defective SLC24A5 causes oculocutaneous albinism 6 (OCA6)
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Body mass index ( 25133637) Cutaneous melanoma or hair colour ( 32341527) Eye color ( 30664655) Eye color (brightness) ( 30664655) Eye color (saturation) ( 30664655) Hair color ( 26926045 30664655) Iris color (a* coordinate) ( 30895295) Iris color (b* coordinate) ( 30895295) Metabolite levels ( 23823483) Skin pigmentation ( 30664655 29195075 28300201 31315583 17999355) Skin reflectance (Melanin index) ( 33600456) Skin, hair and eye pigmentation (multivariate analysis) ( 30664655)
Interacting Genes		1 interacting genes: MEOX2
Entrez ID		283652
HPRD ID		18055
Ensembl ID		ENSG00000188467
Uniprot IDs		Q71RS6
PDB IDs
Enriched GO Terms of Interacting Partners?		Somite Specification Segment Specification Somite Development Embryonic Pattern Specification Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Skeletal Muscle Tissue Development Negative Regulation Of Endothelial Cell Migration Regulation Of Cell Migration Involved In Sprouting Angiogenesis Limb Development Negative Regulation Of Blood Vessel Endothelial Cell Migration Roof Of Mouth Development Regulation Of Blood Vessel Endothelial Cell Migration Striated Muscle Tissue Development Muscle Tissue Development
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